{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T06:46:44Z","timestamp":1784357204729,"version":"3.55.0"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effect of effortful swallow on pharyngeal pressure while swallowing saliva and water using a novel high\u2010resolution manometry (HRM) system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with planned data collection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Nagasaki University Hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Eighteen asymptomatic Japanese adult volunteers were studied. A solid\u2010state HRM assembly with 36 circumferential sensors spaced 1\u00a0cm apart was positioned from the velopharynx to the upper esophagus to record pressures while swallowing. The maximum values of the pressure while swallowing saliva (dry swallowing) and 5\u00a0mL of water were measured at the velopharynx, meso\u2010hypopharynx, and upper esophageal sphincter (UES) with and without effortful swallows.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The maximum values of dry swallowing pressures (mm Hg) at the velopharynx, meso\u2010hypopharynx, and UES were significantly higher with effortful swallow (155.7 \u00b1 59.7, 256.7 \u00b1 78.7, and 276.5 \u00b1 87.5, mean \u00b1 standard deviation) than without it (115.3 \u00b1 60.8, 172.9 \u00b1 57.0, and 195.8 \u00b1 61.3). Those of water swallowing pressures were also statistically higher with effortful swallow (169.3 \u00b1 69.1, 236.6 \u00b1 77.2, and 267.3 \u00b1 79.1) than without it (119.2 \u00b1 59.7, 189.5 \u00b1 70.7, and 221.3 \u00b1 72.7).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present results provide quantitative evidence of effortful swallow as well as physiological information. It also is hoped to be an aid to future clinical and investigative studies.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599810390885","type":"journal-article","created":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T13:38:02Z","timestamp":1293802682000},"page":"16-20","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Influence of Effortful Swallow on Pharyngeal Pressure"],"prefix":"10.1002","volume":"144","author":[{"given":"Kenji","family":"Takasaki","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Umeki","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Hara","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetaka","family":"Kumagami","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruo","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-199812000-00008"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)90847-6"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2005.05.005"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-005-0008-y"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2006.04.019"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-002-0050-y"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.127993"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31817dfd02"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.01.025"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/019459988910000109"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(92)91105-D"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-008-9157-0"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599810390885","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599810390885","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599810390885","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T12:49:37Z","timestamp":1760964577000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599810390885"}},"subtitle":["Evaluation Using a High\u2010Resolution Manometry"],"short-title":[],"issued":{"date-parts":[[2010,12,31]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1177\/0194599810390885"],"URL":"https:\/\/doi.org\/10.1177\/0194599810390885","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,31]]},"assertion":[{"value":"2010-06-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-09-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-12-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}