{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T19:38:25Z","timestamp":1783798705727,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,12,29]],"date-time":"2010-12-29T00:00:00Z","timestamp":1293580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To document the prevalence of secondary airway lesions (SALs) among children with laryngomalacia (LM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>A cross\u2010sectional observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Single practice in a tertiary care pediatric facility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Patients diagnosed with LM were initially identified from a prospectively kept surgical database. Patients with cardiac\/large\u2010vessel malformations, prematurity, repeated or prolonged intubations, acute infections, or prior airway surgery were excluded. Only children who had a full examination of the airway were included. Other associated diagnoses along with demographics, surgical intervention, and type of LM were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Over an 8\u2010year period, 1112 patients underwent laryngoscopy and bronchoscopy. A total of 108 consecutive cases were diagnosed with LM (78 primary diagnosis and 30\u00a0secondary diagnosis). After excluding 17 with disorders associated with large airway disease, 91\u00a0LM patients were included. The mean age was 553.23\u00a0days (ranging between 5\u00a0days and 15 years); 60 were boys and 31 were girls. The prevalence of SALs was 7.7% (95% confidence interval, 7.65\u20107.76; 7 children; 4 subglottic stenosis, 4 tracheomalacia, 1 bronchomalacia, and 1 choanal atresia). Fifty\u2010nine patients underwent supraglottoplasties, while 1 patient had a tracheostomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>After accounting for conditions known to be associated with large airway lesions, the prevalence of SALs associated with laryngomalacia was much less than previously reported. The authors hypothesize that the upper\u2010end figures are a reflection of highly select cohorts and the inclusion of patients with other pathology known to be associated with subglottic stenosis, tracheomalacia, and bronchomalacia and low thresholds for diagnosing mild subglottic stenosis.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599810391600","type":"journal-article","created":{"date-parts":[[2010,12,30]],"date-time":"2010-12-30T05:20:12Z","timestamp":1293686412000},"page":"268-273","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Secondary Airway Lesions in Laryngomalacia"],"prefix":"10.1002","volume":"144","author":[{"given":"Hani A.","family":"Rifai","sequence":"first","affiliation":[{"name":"Pediatric Otolaryngology Divisions of Pediatric Surgery and Otolaryngology Department of Surgery The Stollery Children\u2019s Hospital &amp; University of Alberta Hospitals Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Benoit","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry University of Alberta Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamdy","family":"El\u2010Hakim","sequence":"additional","affiliation":[{"name":"Pediatric Otolaryngology Divisions of Pediatric Surgery and Otolaryngology Department of Surgery The Stollery Children\u2019s Hospital &amp; University of Alberta Hospitals Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,29]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348948409300502"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199003000-00013"},{"key":"e_1_2_7_4_2","first-page":"397","article-title":"Etiology of stridor in the neonate, infant and child","volume":"89","author":"Holinger LD","year":"1980","journal-title":"Ann Otol"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199911000-00009"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009900807"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2007.12.001"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348948709600118"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348948709600119"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2008.01.002"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.06.003"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348940911800107"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.73"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.7.672"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(87)90026-7"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(96)01454-1"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949410300410"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200207000-00019"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1258\/0022215011906966"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348947708600502"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890150076014"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599810391600","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599810391600","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599810391600","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:50:30Z","timestamp":1760961030000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599810391600"}},"subtitle":["A Different Perspective"],"short-title":[],"issued":{"date-parts":[[2010,12,29]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["10.1177\/0194599810391600"],"URL":"https:\/\/doi.org\/10.1177\/0194599810391600","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,29]]},"assertion":[{"value":"2010-09-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-11-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-12-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}