{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T11:26:11Z","timestamp":1788780371104,"version":"build-2803163510"},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,2,3]],"date-time":"2011-02-03T00:00:00Z","timestamp":1296691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to document the rate of pathologic neck disease in patients presenting with metastatic cutaneous squamous cell carcinoma (CSCC) to the parotid gland following parotidectomy and neck dissection in the clinically and radiologic negative neck.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>The study involved a retrospective chart review from 1999 to 2008 of patients presenting with metastatic CSCC to the parotid at the Princess Alexandra Hospital, Brisbane, Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty\u2010one patients with metastatic parotid disease were identified. A total of 51 (63%) patients had no clinical or radiological evidence of cervical nodal disease. Forty\u2010five patients (88%) were male, median age was 69 (range, 42\u201091) years, and the median follow\u2010up was 16 (interquartile range, 9\u201044) months. Thirty\u2010four of these patients underwent a parotidectomy and neck dissection with\/without postoperative radiotherapy (RT). Occult pathological cervical nodal disease was found in 5 (14.7%) patients. Of those who received a neck dissection, 3 patients relapsed in the parotid, 1\u00a0in the neck alone, and 1 distantly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This series has shown that the rate of pathologically involved neck nodes in patients with metastatic CSCC to the parotid in the clinically node negative neck is low. Given many of these patients warrant postoperative RT to the parotid bed, an elective neck dissection may not be warranted as the parotid and neck may be treated in continuity with RT.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599810395361","type":"journal-article","created":{"date-parts":[[2011,2,3]],"date-time":"2011-02-03T22:46:33Z","timestamp":1296773193000},"page":"549-551","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Pathologic Occult Neck Disease in Patients With Metastatic Cutaneous Squamous Cell Carcinoma to the Parotid"],"prefix":"10.1002","volume":"144","author":[{"given":"Diana N.","family":"Kirke","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head &amp; Neck Surgery Princess Alexandra Hospital Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Porceddu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Princess Alexandra Hospital Brisbane Queensland Australia"},{"name":"University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin D.","family":"Wallwork","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head &amp; Neck Surgery Princess Alexandra Hospital Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedict","family":"Panizza","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head &amp; Neck Surgery Princess Alexandra Hospital Brisbane Queensland Australia"},{"name":"University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William B.","family":"Coman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head &amp; Neck Surgery Princess Alexandra Hospital Brisbane Queensland Australia"},{"name":"University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,2,3]]},"reference":[{"key":"e_1_2_9_2_2","volume-title":"Basal Cell Carcinoma, Squamous Cell Carcinoma (and Related Lesions): A Guide to Clinical Management in Australia","year":"2008"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1992.tb07065.x"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20576"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20048"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02737.x"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20360"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000173202.56739.9f"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.1106"},{"issue":"2","key":"e_1_2_9_10_2","first-page":"107","article-title":"Dose response relationship for elective neck irradiation of head and neck cancer: facts and controversies","volume":"45","author":"Suwinski R","year":"1998","journal-title":"Neoplasma"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599810395361","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599810395361","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599810395361","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:36:56Z","timestamp":1760971016000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599810395361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,3]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1177\/0194599810395361"],"URL":"https:\/\/doi.org\/10.1177\/0194599810395361","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,3]]},"assertion":[{"value":"2010-09-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-12-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}