{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:46:41Z","timestamp":1761007601628,"version":"build-2065373602"},"reference-count":5,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,3,31]],"date-time":"2011-03-31T00:00:00Z","timestamp":1301529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:p>Mycotoxins are toxic secondary metabolites produced by a variety of fungi including <jats:italic>Aspergillus<\/jats:italic>, <jats:italic>Alternaria<\/jats:italic>, and <jats:italic>Penicillium<\/jats:italic> species. The presence of mycotoxins in sinonasal tissue and secretions and any possible link to chronic rhinosinusitis (CRS) or other diseases of the head and neck have not been reported. The authors performed an exploratory study to determine the presence and levels of mycotoxins in the sinonasal tissue and secretions of 18 subjects undergoing endoscopic sinus surgery for CRS. Using commercial enzyme\u2010linked immunosorbent assay kits, samples were analyzed for the following mycotoxins: aflatoxin, deoxynivalenol, zearalenone, ochratoxin, and fumonisin. All specimens were negative for aflatoxin, deoxynivalenol, zearalenone, and fumonisin. Four (22%) of 18 specimens were positive for ochratoxin. The clinical significance of this finding remains to be determined.<\/jats:p>","DOI":"10.1177\/0194599811403891","type":"journal-article","created":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:13:42Z","timestamp":1301616822000},"page":"327-329","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Measurement of Mycotoxins in Patients with Chronic Rhinosinusitis"],"prefix":"10.1002","volume":"145","author":[{"given":"Seth M.","family":"Lieberman","sequence":"first","affiliation":[{"name":"New York University School of Medicine Department of Otolaryngology New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph B.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"New York University School of Medicine Department of Otolaryngology New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard A.","family":"Lebowitz","sequence":"additional","affiliation":[{"name":"New York University School of Medicine Department of Otolaryngology New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew B.","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"New York University School of Medicine Department of Otolaryngology New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Crawford","sequence":"additional","affiliation":[{"name":"New York University School of Medicine New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard A.","family":"Feigenbaum","sequence":"additional","affiliation":[{"name":"New York University School of Medicine Departments of Medicine and Otolaryngology New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,31]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.4065\/74.9.877"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200302000-00013"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.07.058"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfm102"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0272-0590(90)90230-H"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599811403891","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599811403891","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599811403891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:27:18Z","timestamp":1760970438000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599811403891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,31]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["10.1177\/0194599811403891"],"URL":"https:\/\/doi.org\/10.1177\/0194599811403891","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2011,3,31]]},"assertion":[{"value":"2010-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-02-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-03-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}