{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:16:13Z","timestamp":1790820973836,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,1,11]],"date-time":"2012-01-11T00:00:00Z","timestamp":1326240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The asymmetry ratio of ocular vestibular\u2010evoked myogenic potential (oVEMP) &gt;40% is interpreted as augmented or reduced response depending on whether the nI\u2010pI amplitude of the lesion ear is larger or smaller than that of the opposite ear, respectively. This study compared unilateral M\u00e9ni\u00e8re disease patients with augmented oVEMPs vs reduced oVEMPs to elucidate the mechanism of augmented oVEMP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty patients with unilateral definite M\u00e9ni\u00e8re disease were enrolled in this study, including 20 patients with augmented oVEMPs and another 20 patients with reduced oVEMPs in the hydropic side. All patients underwent audiometry, caloric test, and oVEMP and cervical VEMP (cVEMP) tests via bone\u2010conducted vibration stimuli. Then, the oVEMP and cVEMP test results were compared with the stage of M\u00e9ni\u00e8re disease, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The augmented group had earlier nI and pI latencies and larger nI\u2010pI amplitude of oVEMPs compared with the reduced group. Caloric test also revealed a significant difference in abnormal responses between the augmented and reduced groups. However, both groups did not differ significantly in the abnormal percentage of cVEMP test results. A significant trend to decline in the prevalence of augmented oVEMPs was noted from stages I to III\u2010IV but not in that of abnormal cVEMPs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The augmented oVEMPs have earlier latencies and larger amplitudes compared with the reduced oVEMPs, indicating that a relatively larger population of intact utricular afferents is activated during the early stage of M\u00e9ni\u00e8re disease.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599811433982","type":"journal-article","created":{"date-parts":[[2012,1,12]],"date-time":"2012-01-12T01:23:24Z","timestamp":1326331404000},"page":"797-803","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Augmentation of Ocular Vestibular\u2010Evoked Myogenic Potentials via Bone\u2010Conducted Vibration Stimuli in M\u00e9ni\u00e8re 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