{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T23:46:20Z","timestamp":1776815180709,"version":"3.51.2"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T00:00:00Z","timestamp":1335744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To study the relationship between peritonsillar abscess (PTA) and minor salivary glands surrounding the palatine tonsils.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective population\u2010based study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Settings<\/jats:title><jats:p>Tertiary care university hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Method<\/jats:title><jats:p>Prospective study including 41 patients with PTA and 6 patients with a neck abscess. Amylase levels of the pus and serum were measured and compared between the 2\u00a0groups. Clinical data regarding hospitalization length and recurrence rate were also collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 41 patients with PTA, 7 suffered from recurrent PTA. Average level of amylase in the pus of the PTA group was 3841 U\/L versus 7.7 U\/L in the neck abscess group (<jats:italic>P<\/jats:italic> &lt;. 001; median, 62 vs 9.5). Serum amylase was higher in the PTA group (49.3 U\/L vs 37.3 U\/L; <jats:italic>P<\/jats:italic> =. 008). There were no recurrences in PTA patients with amylase greater than 65 U\/dL in the pus in 0 of 20 (0%) versus 7 of 21 (33%) for amylase lower than 65 U\/L (<jats:italic>P<\/jats:italic> =. 01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>High amylase in the pus lends further support for involvement of minor salivary glands. However, high recurrence rates related to low amylase in the pus imply an additional pathogenesis possibly related to tonsillar infection. It is possible that both minor salivary glands as well as tonsillar infection play a role in the pathogenesis of peritonsillar infections.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599812445552","type":"journal-article","created":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T01:37:38Z","timestamp":1335836258000},"page":"472-474","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Involvement of Minor Salivary Glands in the Pathogenesis of Peritonsillar Abscess"],"prefix":"10.1002","volume":"147","author":[{"given":"Sabri","family":"El\u2010Saied","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Soroka University Medical Center Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Puterman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Soroka University Medical Center Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Soroka University Medical Center Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merav","family":"Cohen\u2010Lahav","sequence":"additional","affiliation":[{"name":"Clinical Research Center Soroka University Medical Center Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben\u2010Zion","family":"Joshua","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Soroka University Medical Center Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,30]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-010-1114-9"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-006-0059-8"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.12.043"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811415802"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2008.12.003"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.04.021"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199402000-00011"},{"key":"e_1_2_9_9_2","first-page":"371","article-title":"Distribution of minor salivary glands in the peritonsillar space","volume":"84","author":"Kraitrakul S","year":"2001","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_9_10_2","first-page":"245","article-title":"Investigation of the infectious route of peritonsillar abscess [in Chinese]","volume":"32","author":"Chen Z","year":"1997","journal-title":"Zhonghua Er Bi Yan Hou Ke Za Zhi"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.3109\/10408368509165786"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599812445552","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599812445552","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599812445552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:40:46Z","timestamp":1760953246000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599812445552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,30]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["10.1177\/0194599812445552"],"URL":"https:\/\/doi.org\/10.1177\/0194599812445552","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,30]]},"assertion":[{"value":"2011-11-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-03-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-04-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}