{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:35:36Z","timestamp":1761006936944,"version":"build-2065373602"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,8,7]],"date-time":"2012-08-07T00:00:00Z","timestamp":1344297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of the study was to gather information on outcomes and effect sizes of 2 surgical methods of glossectomy by using a grade system and an objective measure of artifacts in micrometers (\u00b5m). The collected data would be used to plan a definitive study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Pilot study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Nineteen patients affected with tongue cancer were consecutively enrolled in a pilot study and treated by partial glossectomy. Eleven patients (57.89%) of group A were treated with monopolar electrocautery, while 8 patients (42.10%) of group B were treated with Harmonic Focus Curved Shears. Specimens were examined by a pathologist blinded to the surgical procedure, using a 4\u2010grade system for margin artifact assessment (margin fragmentation, cautery\/crush artifact, extravascular blood clot, capillary congestion) and for measuring artifact depth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Artifact depth was more relevant in group A (765,633 \u00b5m) than in group B (473,939 \u00b5m). The difference between groups was significant at the 95% confidence interval (<jats:italic>P<\/jats:italic> &lt;. 0001). Margin fragmentation and capillary congestion compared between the 2\u00a0groups were of no significance. There were less cautery\/crush artifacts and extravascular blood clots observed in the harmonic shears group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>When used to perform a partial glossectomy, Harmonic Focus Curved Shears produce less cautery\/crush artifact and a smaller artifact depth compared with monopolar cautery.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599812456966","type":"journal-article","created":{"date-parts":[[2012,8,8]],"date-time":"2012-08-08T01:26:48Z","timestamp":1344389208000},"page":"1076-1082","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Histopathological Assessment in Glossectomy"],"prefix":"10.1002","volume":"147","author":[{"given":"Giovanni","family":"Cristalli","sequence":"first","affiliation":[{"name":"Department of Otolaryngology &amp; Head and Neck Surgery Italian National Cancer Institute Regina Elena Rome 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