{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:23:58Z","timestamp":1760955838012,"version":"build-2065373602"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,12,7]],"date-time":"2012-12-07T00:00:00Z","timestamp":1354838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the clinical characteristics of children with granular myringitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review of children with granular myringitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary care children\u2019s hospitals in Delaware and Florida.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>From July 1, 2006, to June 30, 2011, 15 patients were identified with granular myringitis based on <jats:italic>International Classification of Diseases, Ninth Revision<\/jats:italic> code 384.1 (10\u00a0male, 5 female; 10 left\u2010sided, 5 right\u2010sided).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Average age at onset was 10 years (range, 4\u201018 years). Average length of symptoms was 21\u00a0months (range, 3\u201048\u00a0months). Thirteen of the 15 patients (87%) had myringotomy tube placement prior to diagnosis of myringitis, and 11 had a previous perforation (73%). Eleven myringoplasties were performed on 8 (53%) patients prior to the onset of granular myringitis (5 fascia, 2 fat, 2 cartilage, 1 paper patch, and 1 at an outside hospital that was unknown). A total of 27 otolaryngologic surgical procedures were done on 14 of 15 patients. Ten patients (67%) had audiometry performed, and 6 (40%) had ear cultures. Medical treatment included ciprofloxacin and dexamethasone otic drops in all patients, oral antibiotics in 4 patients, and additional topical agents in 8 patients. Two patients had laser resurfacing, and 1 patient had surgical curettage. Five patients had long\u2010term remission, 8 had intermittent remission, and 2 had no remission of their symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Granular myringitis is a chronic, recalcitrant disease typically preceded by myringotomy and tube placement or myringoplasty\/tympanoplasty. Medical and surgical intervention is varied and often does not lead to permanent resolution of the disease.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599812470433","type":"journal-article","created":{"date-parts":[[2012,12,8]],"date-time":"2012-12-08T03:17:26Z","timestamp":1354936646000},"page":"291-296","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Characteristics of Pediatric Granular Myringitis"],"prefix":"10.1002","volume":"148","author":[{"given":"Jessica R.","family":"Levi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery and Department of Pediatrics Boston University\/Boston Medical Center Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie A.","family":"Ames","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Thomas Jefferson University Hospital Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lyuba","family":"Gitman","sequence":"additional","affiliation":[{"name":"Jefferson Medical College Thomas Jefferson University Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Morlet","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Nemours\/Alfred I. duPont Hospital for Children Wilmington Delaware USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"O\u2019Reilly","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Nemours\/Alfred I. duPont Hospital for Children Wilmington Delaware 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