{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:05:12Z","timestamp":1762430712370,"version":"build-2065373602"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T00:00:00Z","timestamp":1358985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify the prevalence and risk factors of eustachian tube dysfunction after surgery for sinonasal cancer by observing the occurrence of middle ear effusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Historical cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Academic university hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Clinical records of 112 patients surgically treated for sinonasal cancer over a 16\u2010year period were evaluated. Initial bivariate analysis was followed by a multivariate logistic regression model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The best model included 2 variables: posterior extension of surgical resection (nasopharynx, soft palate, eustachian tube, pterygomaxillary fossa, parapharyngeal space) with an odds ratio of 5.662 (95% confidence interval [CI], 1.877\u20109.447) and postoperative radiotherapy with an odds ratio of 8.691 (95% CI, 4.187\u201013.194).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite the limited number of patients, the study gives a prediction of middle ear effusion based on 2 well\u2010defined factors: surgical resection of anatomic structures involved in tubal function and adjuvant radiotherapy.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599812474798","type":"journal-article","created":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T23:00:47Z","timestamp":1359068447000},"page":"619-624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Middle Ear Effusion in Patients with Sinonasal Cancer Treated by Surgery with or without Radiotherapy"],"prefix":"10.1002","volume":"148","author":[{"given":"Luca Oscar","family":"Redaelli de Zinis","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery University of Brescia School of Medicine Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Parrinello","sequence":"additional","affiliation":[{"name":"Section of Medical Statistics University of Brescia School of Medicine Brescia 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