{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T14:23:47Z","timestamp":1778509427074,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T00:00:00Z","timestamp":1394668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005193","name":"American Academy of Otolaryngology-Head and Neck Surgery","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005193","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Children with otitis media (OM) suffer sleep disturbances, loss of appetite, earache, and behavioral problems. Our objective was to quantitate the average burden of OM and to compare the associated impact of tympanostomy tubes on infant health related quality of life (HR\u2010QoL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Multi\u2010institutional prospective cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Otolaryngology, family practice, and pediatric clinics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Children ages 6 to 24\u00a0months of age with or without recurrent OM. Patient history, the PedsQL Infant QoL survey, and the 6\u2010item child with OM survey (Otitis Media 6 [OM\u20106]) were collected from providers and parents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data from 1208 patients were analyzed. Mean age was 14.7\u00a0months, and 54% were male. The mean OM\u20106 score of children with recurrent OM was 3.3, whereas similarly aged well\u2010children had a mean OM\u20106 score of 2.5. The mean PedsQL Infant scores of recurrent OM patients were significantly worse than those of children from well\u2010child visits. Worse OM\u20106 scores were correlated with poorer PedsQL Infant scores, Pearson <jats:italic>r<\/jats:italic> = \u22120.581 (1\u201012\u00a0months) and \u22120.558 (13\u201024\u00a0months), <jats:italic>P<\/jats:italic> &lt;. 001. Otolaryngology patients who were recommended to undergo ear tube placement had significantly poorer OM\u20106 scores and worse PedsQL Infant scores, whereas patients with prior tube placement had significantly better OM\u20106 and PedsQL Infant scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children with recurrent OM had significantly worse HR\u2010QoL than similarly aged healthy children. Increased burden of OM strongly affected HR\u2010QoL, and recommendation for tube placement was associated with increased disease burden and poorer HR\u2010QoL. The presence of tympanostomy tubes was associated with better OM\u20106 and PedsQL Infant scores.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599814525576","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T01:10:25Z","timestamp":1394759425000},"page":"333-340","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Impact of Otitis Media Severity on Children's Quality of Life"],"prefix":"10.1002","volume":"151","author":[{"given":"David J.","family":"Grindler","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Washington University School of Medicine St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J.","family":"Blank","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Washington University School of Medicine St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristine A.","family":"Schulz","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Duke University School of Medicine Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Witsell","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Duke University School of Medicine Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith E. 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