{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:29:08Z","timestamp":1761006548305,"version":"build-2065373602"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,8,4]],"date-time":"2014-08-04T00:00:00Z","timestamp":1407110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Learn the molecular resonance (MR) technology for tonsillectomy. An analysis of outcomes of MR compared to standard cold\u2010knife (CK) and monopolar cautery (MPC) for pediatric tonsillectomy offers new possibilities, lowering postoperative morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Eleven\u2010year, prospective, randomized, 3\u2010group trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary care pediatric institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Eight hundred and seventy\u2010three children undergoing adenotonsillectomy were randomly assigned to MR (n = 283), CK (n = 279), or MPC (n = 279) techniques. Outcome measures included intraoperative time, blood loss, postoperative pain, weight loss, and histopathologic examination on excised tonsils.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Histopathologic evaluation revealed reduced thermal injury with MR over MPC (43 \u00b5m vs 186, <jats:italic>P<\/jats:italic> &lt;. 001), statistically associated with reduced muscular, blood vessel, and nerve fiber damage compared to CK (<jats:italic>P<\/jats:italic> &lt;. 001). Blood loss was minimal in MR. Significant reduced pain scores were related to MR (<jats:italic>P<\/jats:italic> &lt;. 002). Two MR, 15 CK, and 12\u00a0MPC patients experienced delayed bleeding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MR for pediatric tonsillectomy resulted in reduced histopathologic thermal injury, lower pain scores, and reduced postoperative morbidity compared with CK and MPC techniques in an 11\u2010year study.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599814545458","type":"journal-article","created":{"date-parts":[[2014,8,5]],"date-time":"2014-08-05T02:25:45Z","timestamp":1407205545000},"page":"861-867","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Molecular Resonance Tonsillectomy in Children: Comparative Study over Standard Techniques in an 11\u2010Year Study"],"prefix":"10.1002","volume":"151","author":[{"given":"Riccardo","family":"D'Eredit\u00e0","sequence":"first","affiliation":[{"name":"Division of Pediatric Otolaryngology Department of Otorhinolaryngology, Head and Neck Surgery Vicenza Civil Hospital Vicenza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"CullenKA HallMJ GolosinskiyA.National health statistics reports Center for Disease Control ambulatory surgery in the United States 2006.www.cdc.gov\/nchs\/data\/nhsr\/nhsr011.pdf. 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