{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:02:21Z","timestamp":1792652541126,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T00:00:00Z","timestamp":1416182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the effectiveness of the endolymphatic duct blockage (EDB) and the endolymphatic sac decompression (ESD) to control M\u00e9ni\u00e8re's disease symptoms and to evaluate their effect on hearing level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective nonblinded randomized study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Fifty\u2010seven patients affected by a refractory M\u00e9ni\u00e8re's disease were included out of which 22 underwent an ESD and 35 underwent an EDB. Five periods of follow\u2010up were considered: 0 to 1 week, 1 week to 6\u00a0months, 6 to 12\u00a0months, 12 to 18\u00a0months, and 18 to 24\u00a0months. Mean outcome measurements consisted of vertigo control, tinnitus, aural fullness, instability, and hearing level. Hearing level was evaluated using pure\u2010tone average (PTA) and speech discrimination score (SDS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference between the 2\u00a0groups in the number of vertigo spells per months preoperatively (<jats:italic>P<\/jats:italic> =. 153). Twenty\u2010four months postoperatively, 96.5% of the EDB group had achieved a complete control of vertigo spells against 37.5% of the ESD group with a statistically significant difference (<jats:italic>P<\/jats:italic> =. 002). There was a better control of tinnitus and aural fullness with EDB (<jats:italic>P<\/jats:italic> =. 021 and <jats:italic>P<\/jats:italic> =. 014, respectively). There was no statistically significant difference in hearing level preoperatively (<jats:italic>P<\/jats:italic> =. 976) and 24\u00a0months postoperatively (<jats:italic>P<\/jats:italic> =. 287) between the 2\u00a0groups. Hearing level was preserved in each group with no significant difference between the preoperative and the postoperative levels (<jats:italic>P<\/jats:italic> &gt;. 05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EDB is more effective than the traditional ESD in controlling the symptoms of M\u00e9ni\u00e8re's disease. It is a novel surgical technique with promising results for a complete treatment of M\u00e9ni\u00e8re's disease. There are no significant complications or adverse effect.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599814555840","type":"journal-article","created":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T00:30:20Z","timestamp":1416270620000},"page":"122-129","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Endolymphatic Duct Blockage: A Randomized Controlled Trial of a Novel Surgical Technique for M\u00e9ni\u00e8re's Disease Treatment"],"prefix":"10.1002","volume":"152","author":[{"given":"Issam","family":"Saliba","sequence":"first","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Montreal University Hospital Center (CHUM) University of Montreal Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Gabra","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Montreal University Hospital Center (CHUM) University of Montreal Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musaed","family":"Alzahrani","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery Montreal University Hospital Center (CHUM) University of Montreal Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamal","family":"Berbiche","sequence":"additional","affiliation":[{"name":"Department of Statistics University of Montreal Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2010.05.003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1000390103"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1927.00610010329001"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1928.01140060002001"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198405000-00020"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980300084-6"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)30695-2"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)30691-5"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)30693-9"},{"key":"e_1_2_8_11_1","volume-title":"Essentials of Neurotology","author":"Kartush J","year":"2002"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.119485"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988910000102"},{"key":"e_1_2_8_14_1","first-page":"85","article-title":"Endolymphatic system shunting: a long\u2010term profile of the Denver Inner Ear Shunt","volume":"17","author":"Jackson CG","year":"1996","journal-title":"Am J Otol"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199709000-00010"},{"key":"e_1_2_8_16_1","first-page":"337","article-title":"The role of endolymphatic mastoid shunt surgery in the managed care era","volume":"19","author":"Pensak ML","year":"1998","journal-title":"Am J Otol"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489109128054"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31821553ce"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181db733e"},{"key":"e_1_2_8_20_1","first-page":"46","article-title":"\u201cOptimized\u201d retrolabyrinthine approach. 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