{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T23:05:36Z","timestamp":1789167936375,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T00:00:00Z","timestamp":1430092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The primary objective of this study is to evaluate the differences in socioeconomic, demographic, and disease severity factors between patients with chronic rhinosinusitis (CRS) and those with allergic fungal rhinosinusitis (AFRS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>A retrospective cohort analysis was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>The study was conducted at the hospital of the University of North Carolina at Chapel Hill.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>A total of 186 patients were included (93 AFRS, 93 CRS with and without nasal polyps). Socio\u2010 economic and demographic data were obtained from the North Carolina State Data Center. Indicators of disease severity were measured by Lund\u2010Mackay scores, serum immunoglobulin E (IgE) levels, diagnosis of asthma and\/or allergic rhinitis, and the number of surgeries and computed tomography scans performed. Associations were analyzed with Fisher\u2019s exact, Wilcoxon rank sum, and Pearson\u2019s correlations tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with patients with AFRS, patients in both CRS groups were predominantly white (<jats:italic>P<\/jats:italic> &lt;. 0001), were older at the time of diagnosis (<jats:italic>P<\/jats:italic> &lt;. 0001), had higher county\u2010based income per capita (<jats:italic>P<\/jats:italic> =. 004), had lower quantitative serum IgE level (<jats:italic>P<\/jats:italic> &lt;. 001), and had lower Lund\u2010Mackay scores (<jats:italic>P<\/jats:italic> &lt;. 0001). No associations between disease severity, socioeconomic status, and demographic factors were found within the CRS groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Within our cohort of patients residing in North Carolina, those with CRS have higher income, more access to primary care, and lower markers of disease severity than those with AFRS. These data continue to support the notion that AFRS merits classification as a distinct subtype of CRS.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599815580978","type":"journal-article","created":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T22:41:30Z","timestamp":1430174490000},"page":"137-143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Comparison of Socioeconomic and Demographic Factors in Patients with Chronic Rhinosinusitis and Allergic Fungal Rhinosinusitis"],"prefix":"10.1002","volume":"153","author":[{"given":"Yemeng","family":"Lu\u2010Myers","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of North Carolina Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison M.","family":"Deal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery 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