{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T18:04:36Z","timestamp":1783101876127,"version":"3.54.6"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,7,27]],"date-time":"2015-07-27T00:00:00Z","timestamp":1437955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To test the following associations: (1) complete obstruction on drug\u2010induced sleep endoscopy (DISE) and polysomnographic and subjective measures of obstructive sleep apnea; (2) tongue base\/epiglottic obstruction and apnea index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Academic medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Subjects included surgically na\u00efve adult patients with DISE. Chart extraction included demographics, polysomnography, and Epworth Sleepiness Scale and SNORE25 (Symptoms of Nocturnal Obstruction and Related Events 25) scores. Each DISE video was examined for complete obstruction at velum, oropharynx, tongue, epiglottis (VOTE system). Student\u2019s <jats:italic>t<\/jats:italic> test, correlation, and multivariate linear regression were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 65 subjects, complete obstruction was observed at 0 (3%), 1 (46%), 2 (48%), and 3 (3%) subsites, respectively. Subjects with 0\u20101 subsites vs 2\u20104 subsites of complete obstruction had similar apnea indexes (13 \u00b1 24 vs 12 \u00b1 17, <jats:italic>P<\/jats:italic> =. 78, 83% power to detect difference of 15), apnea\u2010hypopnea indexes (30 \u00b1 25 vs 31 \u00b1 28, <jats:italic>P<\/jats:italic> =. 96, 54% power to detect difference of 15), Epworth Sleepiness Scale scores (11 \u00b1 7 vs 12 \u00b1 5, <jats:italic>P<\/jats:italic> =. 34, 91% power to detect difference of 5), and SNORE25 scores (2.0 \u00b1 1.1 vs 1.9 \u00b1 1.0, <jats:italic>P<\/jats:italic> =. 70, 96% power to detect difference of 1.0), with similar results after adjusting for age, sex, body mass index, and tonsil status. Neither tongue base nor epiglottic obstruction was associated with apnea index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The number of subsites with complete obstruction on DISE was not associated with polysomnographic, subjective sleepiness, and quality\u2010of\u2010life measures. Tongue base and epiglottic obstruction were not associated with apnea index. Larger detailed analyses are needed to determine the importance of each site and degree of obstruction seen on DISE.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599815595808","type":"journal-article","created":{"date-parts":[[2015,7,27]],"date-time":"2015-07-27T21:40:29Z","timestamp":1438033229000},"page":"875-880","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Association between Drug\u2010Induced Sleep Endoscopy and Measures of Sleep Apnea Burden"],"prefix":"10.1002","volume":"153","author":[{"given":"Raj C.","family":"Dedhia","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Washington School of Medicine Seattle Washington USA"},{"name":"Division of Pulmonary and Critical Care Medicine University of Washington School of Medicine Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward 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role of drug\u2010induced sleep endoscopy in the diagnosis and management of obstructive sleep apnoea syndrome: our personal experience","volume":"33","author":"De Corso E","year":"2013","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_8_14_1","article-title":"Effect of different oxygen desaturation threshold levels on hypopnea scoring and classification of severity of sleep apnea","author":"Myllymaa S","journal-title":"Sleep 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