{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T11:19:02Z","timestamp":1779275942140,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,8,25]],"date-time":"2015-08-25T00:00:00Z","timestamp":1440460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To review our experience with the diagnosis and treatment of irritant\u2010induced paradoxical vocal fold motion disorder (IPVFMD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary academic referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Thirty\u2010four cases that met IPVFMD criteria and 76 cases of non\u2010IPVFMD were selected from a database of patients with paradoxical vocal fold motion disorder\u2014the diagnosis of which was made on the basis of flexible fiberoptic laryngoscopy and augmented by an odor challenge. Clinical charts were reviewed to document history of environmental allergies, pulmonary disease, gastroesophageal reflux, psychiatric disorder, fibromyalgia, tobacco use, alcohol use, dysphonia, cough, dysphagia, and treatment outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no statistical differences between the IPVFMD and non\u2010IPVFMD groups. Of the patients who were assigned and attended laryngeal control therapy, 13 (65%) reported improvement of symptoms. Symptom improvement increased to 100% in those patients who attended at least 2 laryngeal control therapy sessions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>IPVFMD should be considered in patients presenting with respiratory symptoms after irritant exposure. Sensitivity of diagnosis can be improved via a standardized approach consisting of a careful history and physical examination, including laryngoscopy in the presence of triggers. Laryngeal control therapy is a well\u2010tolerated and effective method of managing IPVFMD.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599815600144","type":"journal-article","created":{"date-parts":[[2015,8,25]],"date-time":"2015-08-25T22:33:57Z","timestamp":1440542037000},"page":"996-1000","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Irritant\u2010Induced Paradoxical Vocal Fold Motion Disorder"],"prefix":"10.1002","volume":"153","author":[{"given":"Anna M.","family":"Marcinow","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Group Health Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Speech and Language Pathology Wexner Medical Center at The Ohio State University Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Arick","family":"Forrest","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Wexner Medical Center at The Ohio State University Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad W.","family":"deSilva","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Wexner Medical Center at The Ohio State University Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,8,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198306303082605"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.98.5.971"},{"issue":"5","key":"e_1_2_9_4_1","first-page":"1","article-title":"Vocal cord dysfunction","volume":"11","author":"Brugman SM","year":"1993","journal-title":"Med Sci Update"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(00)80099-5"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1006358"},{"key":"e_1_2_9_7_1","first-page":"341","article-title":"Spectrum of presentation of paradoxical vocal cord motion in ambulatory patients","volume":"74","author":"O\u2019Connell MA","year":"1995","journal-title":"Ann Allergy Asthma Immunol"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62492-1"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-199802000-00009"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61341-5"},{"issue":"2","key":"e_1_2_9_11_1","first-page":"ii126","article-title":"The effectiveness of speech and language therapy in vocal cord dysfunction","volume":"61","author":"Pargeter NJ","year":"2006","journal-title":"Thorax"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23176"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2944"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.6.1988"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.1.ats11-99"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-5231(02)00032-1"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2478\/v10001-009-0038-z"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1120"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1012672"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9924(88)90024-X"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599815600144","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599815600144","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599815600144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:14:20Z","timestamp":1760955260000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599815600144"}},"subtitle":["Diagnosis and Management"],"short-title":[],"issued":{"date-parts":[[2015,8,25]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1177\/0194599815600144"],"URL":"https:\/\/doi.org\/10.1177\/0194599815600144","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,25]]},"assertion":[{"value":"2015-02-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-07-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-08-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}