{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T13:45:16Z","timestamp":1783604716370,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,2,23]],"date-time":"2016-02-23T00:00:00Z","timestamp":1456185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate incidence of complications and hospital readmission as a result of ultrasound\u2010guided botulinum toxin injections to manage sialorrhea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Children\u2019s Hospital of Wisconsin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>A case series with chart review was performed of all cases of ultrasound\u2010guided injection of botulinum toxin by pediatric otolaryngologists from March 5, 2010, to September 26, 2014,. Primary outcomes included complications such as dysphagia, aspiration pneumonia, and motor paralysis. Secondary outcomes included hospitalization, intubation, and nasogastric tube placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 48 patients, 111\u00a0interventions, and 306\u00a0intraglandular injections identified. Botulinum toxin type A and type B were utilized in 4 and 107 operative interventions, respectively. Type A was injected into 4 parotid and 4 submandibular glands, utilizing doses of 20 U per parotid and 30 U per submandibular gland. Type B was injected into 98 parotid and 200 submandibular glands, with average dosing of 923 U per parotid and 1170 U per submandibular gland, respectively. There were 2\u00a0instances of subjectively worsening of baseline dysphagia that self\u2010resolved. No cases were complicated by aspiration pneumonia or motor paralysis. No patients required hospital readmission, intubation, or nasogastric tube placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Prior published data indicated 16% complication incidence with ultrasound\u2010guided injection of botulinum toxin. Our study found a low complication rate (0.6%) with ultrasound\u2010guided injections of botulinum toxin to manage sialorrhea, without cases of aspiration pneumonia or motor paralysis. Of 306\u00a0intraglandular injections, there were 2 cases of worsening baseline subjective dysphagia that self\u2010resolved.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599816629612","type":"journal-article","created":{"date-parts":[[2016,2,23]],"date-time":"2016-02-23T22:43:55Z","timestamp":1456267435000},"page":"924-927","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Safety of Ultrasound\u2010Guided Botulinum Toxin Injections for Sialorrhea as Performed by Pediatric Otolaryngologists"],"prefix":"10.1002","volume":"154","author":[{"given":"Bahbak","family":"Shariat\u2010Madar","sequence":"first","affiliation":[{"name":"Children\u2019s Hospital of Wisconsin Department of Otolaryngology\/Medical College of Wisconsin Children\u2019s Hospital Clinics Building Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert 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