{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:44:11Z","timestamp":1761007451730,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2014R1A2A2A01004325"],"award-info":[{"award-number":["2014R1A2A2A01004325"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008903","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI14C3228"],"award-info":[{"award-number":["HI14C3228"]}],"id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>We evaluated postoperative changes in nasal cavity dimensions and their effects on nasal functions and symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>We studied patients who underwent binostril, 4\u2010hand endoscopic endonasal transsphenoidal approach surgery with the bilateral modified nasoseptal rescue flap technique. Pre\u2010 and postoperative paranasal computed tomography scans were used to assess nasal cavity dimensional changes at 4 levels. We also performed several pre\u2010 and postoperative tests, including the Connecticut Chemosensory Clinical Research Center test and the Cross\u2010Cultural Smell Identification Test (n = 119) to evaluate olfactory functions. Also, the Nasal Obstruction Symptoms Evaluation, the Sino\u2010Nasal Outcome Test\u201320, and a visual analog scale were used (n = 157) to record subjective symptoms. We compared these data with the pre\u2010 and postoperative nasal cavity dimensions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two\u2010dimensional objective increases in nasal passage dimensions were evident postoperatively (all cross\u2010sectional areas, <jats:italic>P<\/jats:italic> &lt;. 001, except choana and left inferior turbinate). However, these did not correlate with subjectively assessed symptoms (Nasal Obstruction Symptoms Evaluation, all cross\u2010sectional areas, <jats:italic>P<\/jats:italic> \u2265. 05, except right middle turbinate; Sino\u2010Nasal Outcome Test\u201320, all cross\u2010sectional areas, <jats:italic>P<\/jats:italic> \u2265. 05) or olfactory dysfunction evaluated with the Connecticut Chemosensory Clinical Research Center test (all cross\u2010sectional areas, <jats:italic>P<\/jats:italic> \u2265. 05) or the Cross\u2010Cultural Smell Identification Test (all cross\u2010sectional areas, <jats:italic>P<\/jats:italic> \u2265. 05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Endoscopic endonasal transsphenoidal approach surgery altered the patients\u2019 nasal anatomy, but the changes in nasal cavity dimensions did not affect nasal functions and symptoms. These results will help surgeons to appropriately expose the surgical field during endoscopic endonasal transsphenoidal approach surgery.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599816630726","type":"journal-article","created":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T22:13:59Z","timestamp":1456870439000},"page":"1132-1137","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Anatomic Changes Caused by Endoscopic Endonasal Transsphenoidal Surgery and Their Effects on Nasal Functions"],"prefix":"10.1002","volume":"154","author":[{"given":"Do Hyun","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Seoul St Mary\u2019s Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong\u2010Kil","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Seoul St Mary\u2019s Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sin\u2010Soo","family":"Jeun","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Seoul St Mary\u2019s Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Jin","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Seoul St Mary\u2019s Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Whan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Seoul St Mary\u2019s Hospital College of Medicine The Catholic University of Korea Seoul 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