{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:39:14Z","timestamp":1791913154859,"version":"4.3.4"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,22]],"date-time":"2016-07-22T00:00:00Z","timestamp":1469145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study investigated the effects of continuous positive airway pressure (CPAP) on middle ear pressure and acoustic stapedial reflex and the correlation between CPAP and middle ear pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary hospitals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Fifty patients with obstructive sleep apnea\u2010hypopnea syndrome were assigned to the study group, and 50 healthy volunteers were assigned to the control group. The subjects underwent standard tympanometry while wearing a CPAP device (ie, simulated CPAP treatment), which was set to 0, 5, 10, and 15\u00a0cm H<jats:sub>2<\/jats:sub>O, respectively. Tympanometry was performed before and after swallowing at each pressure of CPAP treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean middle ear pressures were 21.2, 22.6, 22.7, and 23.4 daPa (before swallowing) and 21.6, 42.6, 81.4, and 118.6 daPa (after swallowing) in the study group and 17.6, 18.7, 19.5, and 20.8 daPa (before swallowing) and 17.7, 44.2, 85.6, and 120.5 daPa (after swallowing) in the control group at the CPAPs of 0, 5, 10, and 15\u00a0cm H<jats:sub>2<\/jats:sub>O, respectively. While the CPAPs were at 0 and 15\u00a0cm H<jats:sub>2<\/jats:sub>O, the stapedial muscle reflex at 1.0\u00a0kHz did not have a significant difference between the 2\u00a0groups (\u03c7<jats:sup>2<\/jats:sup> = 0.521, <jats:italic>P<\/jats:italic> =. 470). The Pearson correlation coefficient of the CPAP pressure and the middle ear pressure after swallowing was 0.812 (<jats:italic>P<\/jats:italic> &lt;. 001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CPAP affected middle ear pressure and was directly proportional to the pressure of the CPAP. However, CPAP treatment had no significant effect on stapedial muscle reflex.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599816643706","type":"journal-article","created":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T22:55:15Z","timestamp":1461711315000},"page":"307-311","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Effects of Continuous Positive Airway Pressure on Middle Ear Pressure and Acoustic Stapedial Reflex"],"prefix":"10.1002","volume":"155","author":[{"given":"Jinrang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Navy General Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keliang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Navy General Hospital Beijing China"},{"name":"Anhui Medical University Clinical 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