{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:29:41Z","timestamp":1763036981002,"version":"build-2065373602"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,7,22]],"date-time":"2016-07-22T00:00:00Z","timestamp":1469145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the relationship between prognosis of 2 different facial palsies and pretreatment hematologic laboratory values.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Multicenter case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Three tertiary care hospitals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>We examined the clinical records of 468 facial palsy patients who were treated with an antiviral drug in combination with either oral or intravenous corticosteroids in participating hospitals between 2010 and 2014. Patients were divided into a Bell\u2019s palsy group or a Hunt\u2019s palsy group. We used the Yanagihara facial nerve grading system to grade the severity of facial palsy. \u201cRecovery\u201d from facial palsy was defined as achieving a Yanagihara score \u226536 points within 6\u00a0months of onset and having no accompanying facial contracture or synkinesis. We collected information about pretreatment hematologic findings, demographic data, and electrophysiologic test results of the Bell and Hunt group patients who recovered and those who did not. We then compared these data across the 2 palsy groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the Bell\u2019s palsy group, recovered and unrecovered patients differed significantly in age, sex, electroneuronography score, stapedial muscle reflex, neutrophil rate, lymphocyte rate, neutrophil\u2010to\u2010lymphocyte ratio, and initial Yanagihara score. In the Hunt\u2019s palsy group, recovered and unrecovered patients differed in age, electroneuronography score, stapedial muscle reflex, monocyte rate, platelet count, mean corpuscular volume, and initial Yanagihara score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pretreatment hematologic findings, which reflect the severity of inflammation and bone marrow dysfunction caused by a virus infection, are useful for predicting the prognosis of facial palsy.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599816646552","type":"journal-article","created":{"date-parts":[[2016,5,10]],"date-time":"2016-05-10T23:24:49Z","timestamp":1462922689000},"page":"581-587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Pretreatment Hematologic Findings as Novel Predictive Markers for Facial Palsy Prognosis"],"prefix":"10.1002","volume":"155","author":[{"given":"Koichiro","family":"Wasano","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Japanese Red Cross Shizuoka Hospital Shizuoka Japan"},{"name":"Department of Otolaryngology, Head and Neck Surgery Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiji","family":"Kawasaki","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Japanese Red Cross Shizuoka Hospital Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayuri","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Japanese Red Cross Shizuoka Hospital Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuta","family":"Tomisato","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Japanese Red Cross Shizuoka Hospital Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiichi","family":"Shinden","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Saiseikai Utsunomiya Hospital Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Saiseikai Utsunomiya Hospital Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shujiro","family":"Minami","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology National Hospital Organization Tokyo Medical Center Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Wakabayashi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology National Hospital Organization Tokyo Medical Center Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaoru","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery Keio University School of Medicine Tokyo 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