{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:01:23Z","timestamp":1791424883627,"version":"4.3.3"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T00:00:00Z","timestamp":1470700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Despite evidence that therapeutic mastoidectomy does not improve outcomes in noncholesteatomatous chronic otitis media, it remains widely performed. An up\u2010to\u2010date systematic review is undertaken and conclusions drawn regarding the best evidence\u2010based practice of its management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Sources<\/jats:title><jats:p>PubMed, Google Scholar, Medline Embase, Cochrane, and Web of Science.<\/jats:p><\/jats:sec><jats:sec><jats:title>Review Method<\/jats:title><jats:p>A combination of the following words was used: <jats:italic>chronic otitis media, chronic suppurative otitis media, COM, CSOM, mastoidectomy, tympanoplasty, atelectasis, retraction, tympanic perforation<\/jats:italic>, and <jats:italic>therapeutic<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 1742 studies, 7 were selected for full analysis with respect to the benefit of mastoidectomy in the management of active and inactive mucosal chronic otitis media. Most were retrospective studies, with 1 prospective randomized controlled trial available. Overall, there was no evidence to support routine mastoidectomy in conjunction with tympanoplasty in chronic otitis media. For ears with sclerotic mastoids, the evidence suggested that there may be some benefit as a staged procedure. Two studies were analyzed for the benefit of mastoidectomy in addition to tympanoplasty for the management of the atelectatic ear (inactive squamous chronic otitis media). The conclusion was also that mastoidectomy added no benefit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Examination of the available literature supports the notion that therapeutic mastoidectomy does not lend any additional benefit to the management of noncholesteatomatous chronic otitis media. This has implications for patient care, both clinically and financially. Further research, ideally in the form of a prospective, multi\u2010institutional, geographically wide, ethnically diverse, randomized controlled trial, is needed to further support this notion.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599816662438","type":"journal-article","created":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T21:33:29Z","timestamp":1470173609000},"page":"914-922","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Therapeutic Mastoidectomy in the Management of Noncholesteatomatous Chronic Otitis Media"],"prefix":"10.1002","volume":"155","author":[{"given":"Aaron","family":"Trinidade","sequence":"first","affiliation":[{"name":"University of Arkansas for Medical Sciences Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua C.","family":"Page","sequence":"additional","affiliation":[{"name":"University of Arkansas for Medical Sciences Little Rock 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