{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:29:15Z","timestamp":1792301355205,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T00:00:00Z","timestamp":1479081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To systematically review the evidence on the effect of vestibular rehabilitation in patients with M\u00e9ni\u00e8re\u2019s disease (MD) on balance and dizziness\u2010related quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>A literature search was conducted in the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Embase, Web of Science, and CINAHL databases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>Articles were reviewed by 2\u00a0independent authors and data were compiled in tables for analysis regarding balance (ie, posturography) and dizziness\u2010specific quality of life in patients with MD. A comprehensive search was performed up to November 2015. Studies on relevance and methodological quality were assessed by means of the Cochrane risk of bias tool. For outcome on balance and quality of life, we calculated mean differences and their 95% confidence intervals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 986 unique studies were retrieved. Five studies, including a total of 498 patients, fulfilled the eligibility criteria, including 2 randomized controlled trials and 3 prospective cohort studies. There was no study with a low risk of bias. We found inconsistent evidence for the effect of vestibular rehabilitation on balance and dizziness\u2010related quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Based on the low quality of the selected studies, it is inconclusive whether there is a positive effect of vestibular rehabilitation in patients with MD on balance and dizziness\u2010related quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0194599816678386","type":"journal-article","created":{"date-parts":[[2016,11,9]],"date-time":"2016-11-09T06:54:02Z","timestamp":1478674442000},"page":"426-434","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Effect of Vestibular Rehabilitation in Patients with M\u00e9ni\u00e8re\u2019s Disease: A Systematic Review"],"prefix":"10.1002","volume":"156","author":[{"given":"Babette F.","family":"van Esch","sequence":"first","affiliation":[{"name":"Apeldoorn Dizziness Centre Gelre Hospital Apeldoorn The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellis S.","family":"van der Scheer\u2010Horst","sequence":"additional","affiliation":[{"name":"Apeldoorn Dizziness Centre Gelre Hospital Apeldoorn The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hester J.","family":"van der Zaag\u2010Loonen","sequence":"additional","affiliation":[{"name":"Apeldoorn Dizziness Centre Gelre Hospital Apeldoorn The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tjasse D.","family":"Bruintjes","sequence":"additional","affiliation":[{"name":"Apeldoorn Dizziness Centre Gelre Hospital Apeldoorn The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Paul G.","family":"van Benthem","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery Leiden University Medical Centre The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)32313-6"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70100-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31826426b9"},{"key":"e_1_2_9_5_1","first-page":"195","volume-title":"Meni\u00e8re\u2019s Disease","author":"Ruckenstein MJ"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"CD003559","article-title":"Diuretics for M\u00e9ni\u00e8re\u2019s disease or syndrome","author":"Burgess A","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"e_1_2_9_7_1","first-page":"CD001873","article-title":"Betahistine for Meniere\u2019s disease or syndrome","author":"James AL","year":"2001","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_8_1","first-page":"CD005395","article-title":"Surgery for Meniere\u2019s disease","volume":"2","author":"Pullens B","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489609137819"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-35552010000500003"},{"key":"e_1_2_9_11_1","volume-title":"Vestibular Rehabilitation","author":"Herdman SJ","year":"2007"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(98)70195-0"},{"issue":"2","key":"e_1_2_9_13_1","first-page":"CD005397","article-title":"Vestibular rehabilitation for unilateral peripheral vestibular dysfunction","author":"Hillier SL","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.06.006"},{"key":"e_1_2_9_15_1","unstructured":"HigginsJPT GreenS eds.Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0[updatedMarch 2011]. 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