{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:57:04Z","timestamp":1787907424774,"version":"build-2784847793"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,1,24]],"date-time":"2017-01-24T00:00:00Z","timestamp":1485216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study is to (1) assess incidence of long\u2010term velopharyngeal insufficiency (VPI) and (2) determine other sequelae following classic and modified uvulopalatopharyngoplasty (UPPP and mUPPP) for treatment of obstructive sleep apnea (OSA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Sources<\/jats:title><jats:p>Medline, PubMed, Cochrane Library database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Review Methods<\/jats:title><jats:p>A systematic review was performed following standard Preferred Reporting Items for Systematic Reviews and Meta\u2010analyses (PRISMA) guidelines. Original research articles reporting on sequelae of UPPP and mUPPP for treatment of OSA, at a mean of 1 year follow\u2010up, were included. Articles were retrieved using keywords <jats:italic>UPPP complications<\/jats:italic> and <jats:italic>UPPP questionnaire<\/jats:italic>. A random\u2010effects model was used for pooling data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 24 studies were included in this review. Complications included VPI (24 studies, n = 191), difficulty swallowing (7 studies, n = 83), taste disturbances (4 studies, n = 10), voice changes (7 studies, n = 46), foreign body (9 studies, n = 427), and dry pharynx (7 studies, n = 150). When pooling all studies together, VPI was the least common sequelae reported in 8.1% of the cases. Foreign body sensation was the most commonly reported sequelae at 31.2%, with difficulty swallowing (17.7%), dry pharynx (23.4%), voice changes (9.5%), and taste disturbances (8.2%) being the most to least likely.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The long\u2010term effectiveness of UPPP and mUPPP is limited by the number of studies reporting short\u2010term follow\u2010up only. Despite this, long\u2010term data suggest that complications such as VPI are more common than previously reported. Other sequelae, such as foreign body sensation, may be one of the most frequently expected complications after UPPP surgery.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599816688646","type":"journal-article","created":{"date-parts":[[2017,1,24]],"date-time":"2017-01-24T08:16:54Z","timestamp":1485245814000},"page":"606-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Long\u2010Term Incidence of Velopharyngeal Insufficiency and Other Sequelae following Uvulopalatopharyngoplasty"],"prefix":"10.1002","volume":"156","author":[{"given":"Jessica A.","family":"Tang","sequence":"first","affiliation":[{"name":"Chicago ENT: Advanced Center for Specialty Care Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna M.","family":"Salapatas","sequence":"additional","affiliation":[{"name":"Chicago ENT: Advanced Center for Specialty Care Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren B.","family":"Bonzelaar","sequence":"additional","affiliation":[{"name":"Chicago ENT: Advanced Center for Specialty Care Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Friedman","sequence":"additional","affiliation":[{"name":"Chicago ENT: Advanced Center for Specialty Care Chicago Illinois USA"},{"name":"Rush University Medical Center Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.3.375"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2746"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200708-119MG"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988108900609"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/33.10.1408"},{"key":"e_1_2_8_7_1","first-page":"27","article-title":"Effects and side\u2010effects of surgery for snoring and obstructive sleep apnea\u2014a systematic review","volume":"32","author":"Franklin KA","year":"2009","journal-title":"Sleep"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.5402\/2012\/181202"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1808-86942011000500007"},{"key":"e_1_2_8_10_1","first-page":"185","article-title":"Are too many septal deviations operated on? 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