{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:18:28Z","timestamp":1792819108605,"version":"4.5.0"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,3,28]],"date-time":"2017-03-28T00:00:00Z","timestamp":1490659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine if tonsillectomy alone is an effective treatment in improving obstructive sleep apnea in adult subjects with tonsillar hypertrophy and to evaluate the effect of tonsillectomy on patient\u2010reported quality\u2010of\u2010life indices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with planned data collection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Academic hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Thirty\u2010four subjects completed enrollment and intervention from January 2011 to January 2016. Subjects completed pre\u2010 and postoperative quality\u2010of\u2010life questionnaires, including the Insomnia Severity Index, Epworth Sleepiness Scale, and the Functional Outcomes of Sleep Questionnaire\u201310. Surgical response to treatment was defined by a &gt;50% decrease in the Apnea\u2010Hypopnea Index and a decrease in the overall Apnea\u2010Hypopnea Index to &lt;20. Wilcoxon matched\u2010pairs signed\u2010rank tests were used to test each variable to assess for a change from pre\u2010 to postintervention. Subjects were then split into 3 BMI subgroups, with results also evaluated by Wilcoxon matched\u2010pairs signed\u2010rank tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant difference discovered between the mean preoperative Apnea\u2010Hypopnea Index of 31.57 and the mean postoperative value of 8.12 (<jats:italic>P<\/jats:italic> &lt;. 001). All patient\u2010reported outcomes improved significantly following tonsillectomy. After stratifying all outcome variables (Apnea\u2010Hypopnea Index, Epworth Sleepiness Scale, Insomnia Severity Index, and Functional Outcomes of Sleep Questionnaire\u201310) by sex, race, and tonsil size, no statistically significant difference was noted among any of these subgroups. There was a 78% surgical response to treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tonsillectomy appears to be an effective treatment for obstructive sleep apnea in a select population of adults with tonsillar hypertrophy.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599817698671","type":"journal-article","created":{"date-parts":[[2017,3,28]],"date-time":"2017-03-28T08:08:57Z","timestamp":1490688537000},"page":"331-335","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["The Role of Tonsillectomy in Adults with Tonsillar Hypertrophy and Obstructive Sleep Apnea"],"prefix":"10.1002","volume":"157","author":[{"given":"Matthew M.","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Pediatric Otolaryngology\u2013Head and Neck Surgery Cincinnati Children\u2019s Hospital Medical Center Cincinnati Ohio 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