{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:06:28Z","timestamp":1766048788579,"version":"build-2065373602"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,3,28]],"date-time":"2017-03-28T00:00:00Z","timestamp":1490659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>(1) Describe the prevalence of radiographic signs of intracranial hypertension (ICH) in M\u00e9ni\u00e8re\u2019s disease (MD) and (2) compare the prevalence of radiographic signs of ICH in MD patients managed medically to those managed surgically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case\u2010control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Academic neurotologic practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Adult MD patients (aged \u226517 years) treated from 2011 to 2015 were reviewed. Inclusion required magnetic resonance imaging (MRI) of the head and follow\u2010up &gt;6\u00a0months. Patients with intracranial tumors, mass effect, trauma, previous intracranial surgery, and glaucoma were excluded. MD patients were separated by administered treatment into medical and surgical subgroups. Cochlear implant (CI) recipients served as radiographic controls. Eighty\u2010four MD patients (46 surgical, 38\u00a0medical) and 37 CI controls were assessed. MRI measurements assessed for empty\/partial sella (ES\/PS), dilated\/tortuous optic nerve sheath (ONS), and posterior globe flattening (PGF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 53.8 \u00b1 1.3 years and median body mass index (BMI) was 28.2\u00a0kg\/m<jats:sup>2<\/jats:sup>. Of the patients, 64% were female and 92% were white. MRI findings in the MD cohort were as follows: ES\/PS, 46.4%; ONS change, 42.8%; and PGF, 8.3%. The prevalence of ONS change was higher in MD patients than in controls (42.8% vs 13.5%, <jats:italic>P<\/jats:italic> =. 003). The surgical MD group had higher prevalence of ONS change (52%) compared with the medical group (31.5%, <jats:italic>P<\/jats:italic> =. 05) and controls (13.5%, <jats:italic>P<\/jats:italic> =. 0004). The surgical group had a higher prevalence of \u22652 simultaneous MRI findings compared with medical MD patients (39% vs 10%, <jats:italic>P<\/jats:italic> =. 01) and controls (14%, <jats:italic>P<\/jats:italic> =. 01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MD patients demonstrate a high prevalence of radiographic signs of ICH. MD patients who required surgery had a greater prevalence of radiographic signs of ICH compared with non\u2010MD patients and medically managed MD patients.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599817699401","type":"journal-article","created":{"date-parts":[[2017,3,28]],"date-time":"2017-03-28T08:46:41Z","timestamp":1490690801000},"page":"260-268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Radiographic Evidence of Occult Intracranial Hypertension in Patients with M\u00e9ni\u00e8re\u2019s Disease"],"prefix":"10.1002","volume":"157","author":[{"given":"Kareem O.","family":"Tawfik","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shawn M.","family":"Stevens","sequence":"additional","affiliation":[{"name":"Department of 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