{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:06:41Z","timestamp":1771045601463,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,7]],"date-time":"2017-11-07T00:00:00Z","timestamp":1510012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study was performed to determine whether the efficacy and safety of medical management of uncomplicated peritonsillar abscess (PTA) presenting in the emergency department is equivalent to medical plus surgical therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Southern California Permanente Medical Group (SCPMG).<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Upon successful completion of a prospective study comparing medical treatment (MT) to surgical treatment (ST) of PTA in 2008, MT was adopted by 12 SCPMG centers while 7 centers continued standard surgical drainage. Clinical outcomes are now reviewed on a random sampling of 211 patients with PTA treated with MT and 96 patients treated with ST between 2008 and 2013 at the respective medical centers. Patients were treated with intravenous (IV) fluids, weight\u2010appropriate IV ceftriaxone, clindamycin, and dexamethasone, and then discharged on clindamycin \u00d7 10\u00a0days (MT). Patients in the ST group received MT but also surgical drainage. Primary end points were complication rates and failure rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>MT and ST resulted in no significant difference in treatment success or complications. However, patients in the MT group obtained significantly less liquid opioid prescriptions (MT, 30.8 \u00b1 5.65; ST, 77.75 \u00b1 13.41; <jats:italic>P<\/jats:italic> &lt;. 0001), reported fewer sore days (MT, 4.48 \u00b1 0.27; ST, 5.77 \u00b1 0.49; <jats:italic>P<\/jats:italic> =. 0004), and required less days off from work (MT, 3.4 \u00b1 0.44; ST, 4.9 \u00b1 0.82; <jats:italic>P<\/jats:italic> =. 044).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared to ST, MT appears to be equally safe and efficacious, with less pain, opioid use, and days off work, especially if patients with PTA present without trismus. MT for PTAs reduces the possibility of surgical complications, as well as the cost and inconvenience associated with ST.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599817739277","type":"journal-article","created":{"date-parts":[[2017,12,31]],"date-time":"2017-12-31T06:24:01Z","timestamp":1514701441000},"page":"280-286","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Comparison of Medical Therapy Alone to Medical Therapy with Surgical Treatment of Peritonsillar Abscess"],"prefix":"10.1002","volume":"158","author":[{"given":"Alex","family":"Battaglia","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery Southern California Permanente Medical Group San Diego California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raoul","family":"Burchette","sequence":"additional","affiliation":[{"name":"Regional Offices Department of Research and Evaluation Southern California Permanente Medical Group Pasadena California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Hussman","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\/Head and Neck Surgery University of California\u2013San Diego San Diego California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew A.","family":"Silver","sequence":"additional","affiliation":[{"name":"Department Emergency Medicine Southern California Permanente Medical Group San Diego California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery Southern California Permanente Medical Group San Diego California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery Southern California Permanente Medical Group San Diego California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2015.03.002"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199508002-00001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1977.00780240072010"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mjt.00001= 67430.81464.04"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2015.01.021"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489414556083"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2007.01575.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2003.93"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2667-x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3454-z"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-015-3582-0"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1258\/002221504323219563"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24283"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24936"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/014556130608501013"},{"key":"e_1_2_9_17_1","unstructured":"American Academy of Otolaryngology\u2014Head and Neck Surgery. Annual meeting poster session: a randomized prospective trial comparing outcomes of medical versus surgical management of peritonsillar abscesses.www.researchposters.com\/Posters\/AAOHNSF\/AAO2009\/SP147.pdf. Accessed October 4 2009."},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100078828"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-006-0059-8"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.12.043"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/16.Supplement_4.S292"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-010-1130-9"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25960"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-012-2033-5"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599817739277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599817739277","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599817739277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:13:14Z","timestamp":1760955194000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599817739277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,7]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1177\/0194599817739277"],"URL":"https:\/\/doi.org\/10.1177\/0194599817739277","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,7]]},"assertion":[{"value":"2017-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}