{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T04:01:19Z","timestamp":1791518479465,"version":"4.3.4"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T00:00:00Z","timestamp":1523923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to analyze computed tomography (CT) and magnetic resonance (MR) images and to evaluate the maximum standardized uptake value (SUV max) of positron emission tomography (PET)\/CT parameters between sinonasal non\u2010Hodgkin's lymphoma (NHL) and squamous cell carcinoma (SCC), knowing the imaging features that distinguish sinonasal NHL from SCC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University tertiary care facility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>We analyzed the features on CT, MR imaging, and PET\/CT of 78 patients diagnosed with sinonasal NHL or SCC histopathologically. The CT (n = 34), MRI (n = 25), and PET\/CT (n = 33) images of 39 patients with sinonasal NHL and the CT (n = 38), MR (n = 28), and PET\/CT (n = 31) images of 39 patients with SCC were evaluated. The sinonasal NHL was diagnosed as natural killer\/T\u2010cell lymphoma (n = 28) and diffuse large B\u2010cell lymphoma (n = 11).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with sinonasal NHL had a larger tumor volume and higher tumor homogeneity than patients with SCC on T2\u2010weighted and postcontrast MR images. Most of the sinonasal NHL and SCC showed a high degree of enhancement. The apparent diffusion coefficient (ADC) values and adjacent bone destruction were significantly lower in sinonasal NHL than in SCC. However, cervical lymphadenopathy, Waldeyer's ring involvement, and PET\/CT SUV max showed no significant differences between sinonasal NHL and SCC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CT and MR images of sinonasal masses showing a bulky lesion, marked homogeneity, and low ADC values without adjacent bone destruction are more suggestive of sinonasal NHL than SCC.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599818770621","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T04:01:36Z","timestamp":1523937696000},"page":"494-500","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Differential Diagnosis of Sinonasal Lymphoma and Squamous Cell Carcinoma on CT, MRI, and PET\/CT"],"prefix":"10.1002","volume":"159","author":[{"given":"Seok\u2010Hyun","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital Yangsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue\u2010Jean","family":"Mun","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital Yangsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hak\u2010Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology Pusan National University School of Medicine Pusan National University Hospital Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seon Lin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital Yangsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Dong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital Yangsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu\u2010Sup","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Biomedical Research Institute Pusan National University School of Medicine Pusan National University Hospital Busan South 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