{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:24:20Z","timestamp":1763141060897,"version":"build-2065373602"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T00:00:00Z","timestamp":1524528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine if balloon catheter dilation of sinus ostia affects the severity or frequency of headache among patients who have barometric pressure\u2013related \u201csinus\u201d headache.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective single\u2010blinded randomized controlled trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary care medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Subjects with a diagnosis of sinus pressure headache without evidence of mucosal thickening on computed tomography were recruited. Subjects were blinded and randomized to undergo balloon dilation of affected sinus ostia (active treatment) or balloon dilation in the nasal cavity (placebo). Two balloon devices were utilized (Acclarent and Entellus) and outcomes compared. Subjects were followed with pre\u2010 and postprocedure SNOT\u201022 scores (Sinonasal Outcome Test\u201322), HIT\u20106 scores (Headache Impact Test\u20136), and medication utilization logs for 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no statistically significant difference in SNOT\u201022 or HIT\u20106 scores between the arms at any time point. However, both arms experienced statistically and clinically significant decreases in SNOT\u201022 and HIT\u20106 scores from preprocedure to 6\u00a0months postprocedure. There was no statistically significant difference in SNOT\u201022 or HIT\u20106 score reductions between the Entellus and Acclarent devices. There was no statistically significant difference in medication utilization between the groups at any time point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Subjects with sinus pressure headache without evidence of mucosal thickening on computed tomography had no significant difference in outcomes between active treatment (balloon dilation of sinus ostia) and placebo (nasal dilation). Further study on the etiology and effective treatment of barometric pressure \/ \u201csinus\u201d headache is needed.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599818772818","type":"journal-article","created":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T16:10:51Z","timestamp":1524586251000},"page":"178-184","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Randomized Controlled Trial Examining the Effects of Balloon Catheter Dilation on \u201cSinus Pressure\u201d \/ Barometric Headaches"],"prefix":"10.1002","volume":"159","author":[{"given":"Adrienne M.","family":"Laury","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery San Antonio Military Medical Center San Antonio Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip G.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Texas Health at San Antonio San Antonio Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin C.","family":"McMains","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery San Antonio Military Medical Center San Antonio Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2014.12.056"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000344152.56020.94"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.20085"},{"key":"e_1_2_10_5_1","unstructured":"American Academy of Otolaryngology\u2014Head and Neck Surgery.Sinus headaches.http:\/\/www.entnet.org\/content\/sinus\u2010headaches. 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