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As a high\u2010resolution noninvasive imaging technique, OCT offers promise as a diagnostic aid for otologic conditions, such as otitis media, cholesteatoma, and conductive hearing loss. Using OCT vibrometry to image the nanoscale vibrations of the TM and ME as they conduct acoustic waves may detect the location of ossicular chain dysfunction and differentiate between stapes fixation and incus\u2010stapes discontinuity. The capacity of OCT to image depth and thickness at high resolution allows 3\u2010dimensional volumetric reconstruction of the ME and has potential use for reconstructive tympanoplasty planning and the follow\u2010up of ossicular prostheses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for Practice<\/jats:title>\n                    <jats:p>To achieve common clinical use beyond these initial discoveries, future in vivo imaging devices must feature low\u2010cost probe or endoscopic designs and faster imaging speeds and demonstrate superior diagnostic utility to computed tomography and magnetic resonance imaging. While such technology has been available for OCT, its translation requires focused development through a close collaboration between engineers and clinicians.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0194599818775711","type":"journal-article","created":{"date-parts":[[2018,5,22]],"date-time":"2018-05-22T16:20:41Z","timestamp":1527006041000},"page":"424-438","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Optical Coherence Tomography of the Tympanic Membrane and Middle Ear: A Review"],"prefix":"10.1002","volume":"159","author":[{"given":"Hsern Ern Ivan","family":"Tan","sequence":"first","affiliation":[{"name":"Ear Science Institute Australia Subiaco Australia"},{"name":"Ear Sciences Centre School of Medicine The University of Western Australia Nedlands Australia"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Sir Charles Gairdner Hospital Perth 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