{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T03:20:02Z","timestamp":1777000802363,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T00:00:00Z","timestamp":1543276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the impact of untreated deviated nasal septum (DNS) on recalcitrant chronic rhinosinusitis (CRS) among patients undergoing revision endoscopic sinus surgery (ESS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case\u2010control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary academic center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>We performed a retrospective review of 489 patients undergoing revision ESS for CRS at a tertiary academic center. Patients undergoing septoplasty were matched to nonseptoplasty controls based on age and sex. Preoperative Lund\u2010Mackay score (LMS) was compared between cohorts. Linear regression was used to identify predictors of LMS and ostiomeatal complex (OMC) obstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six matched pairs (72 patients) were selected for analysis: 36 undergoing septoplasty and revision ESS and 36 undergoing revision ESS alone. Compared with nonseptoplasty controls, the septoplasty group had a significantly higher average LMS (17.8 vs 14.6, <jats:italic>P<\/jats:italic> =. 02) and a greater rate of OMC obstruction (89% vs 61%, <jats:italic>P<\/jats:italic> &lt;. 01). The septoplasty group also had significantly higher opacification scores in the maxillary (1.5 vs 1.2, <jats:italic>P<\/jats:italic> =. 03) and posterior ethmoid (1.8 vs 1.4, <jats:italic>P<\/jats:italic> =. 02) sinuses. On multivariable analysis, DNS was an independent predictor of LMS (<jats:italic>P<\/jats:italic> =. 02) and OMC obstruction (<jats:italic>P<\/jats:italic> &lt;. 01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Untreated DNS is associated with radiographic markers of CRS severity among patients undergoing revision ESS and may contribute to the multifactorial pathogenesis of persistent CRS.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599818815106","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T19:14:52Z","timestamp":1543346092000},"page":"922-927","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Impact of Septal Deviation on Recurrent Chronic Rhinosinusitis after Primary Surgery: A Matched Case\u2010Control Study"],"prefix":"10.1002","volume":"160","author":[{"given":"Terence","family":"Fu","sequence":"first","affiliation":[{"name":"Division of Rhinology Department of Otolaryngology\u2013Head and Neck Surgery University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Rhinology Department of Otolaryngology\u2013Head and Neck Surgery University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Yip","sequence":"additional","affiliation":[{"name":"Division of Rhinology Department of Otolaryngology\u2013Head and Neck Surgery University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alisha","family":"Jamal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Rhinology Department of Otolaryngology\u2013Head and Neck Surgery University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2004.06.002"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6815-11-4"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.10.009"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-010-1233-z"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20653"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22361"},{"key":"e_1_2_8_8_1","first-page":"299","article-title":"Is septal deviation a risk factor for chronic sinusitis? 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