{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T10:45:54Z","timestamp":1767091554237,"version":"build-2065373602"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T00:00:00Z","timestamp":1554768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To (1) analyze postoperative thyroidectomy outcomes in patients with diabetes mellitus (DM), who are prone to deleterious effects of glucose dysmetabolism, and (2) apply findings to optimize perioperative management of diabetics requiring thyroid surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective database analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>The National Inpatient Sample was queried using <jats:italic>International Classification of Diseases, Ninth Revision, Clinical Modification<\/jats:italic> and Procedure Coding System (PCS) codes for patients with benign or malignant thyroid disease who underwent thyroid surgery between 2002 and 2013. An analysis of demographics, comorbidities, and postoperative outcomes was conducted between a DM vs non\u2010DM cohort using bivariate and multivariate techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 103,842 cases met inclusion criteria; 14.2% were diabetics. Diabetics had significantly higher rates of baseline comorbid chronic pulmonary disease, hypertension, obesity, and anemia. Following thyroidectomy, patients with DM were more likely to have vocal cord paresis or paralysis compared to non\u2010DM patients (2.0% vs 1.3%; <jats:italic>P<\/jats:italic> &lt;. 001). However, when adjusting for demographics and comorbidities, there was no significant difference in this complication between the 2\u00a0groups. Diabetics had independently higher rates of cardiac, pulmonary, and urinary complications, as well as transfusion, reintubation, and in\u2010hospital mortality. Diabetics had longer hospital stays (2.76 vs 1.97; <jats:italic>P<\/jats:italic> &lt;. 001) with higher incurred hospital charges (32,921 vs 25,198; <jats:italic>P<\/jats:italic> &lt;. 001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although DM often confers metabolic and ischemic derangements secondary to hyperglycemia such as neuropathy, this comorbidity was not independently associated with higher rates of vocal cord paresis or paralysis following thyroid surgery. However, DM predicted other adverse outcomes, including greater cardiac, pulmonary, and urinary complications, as well as transfusion, reintubation, and in\u2010hospital mortality.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599819835793","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T04:11:29Z","timestamp":1554783089000},"page":"46-51","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Thyroidectomy Complications in Patients with Diabetes Mellitus"],"prefix":"10.1002","volume":"161","author":[{"given":"Sei Y.","family":"Chung","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Weill Cornell Medicine New York Presbyterian Hospital New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aparna","family":"Govindan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and 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