{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:34:36Z","timestamp":1792510476822,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T00:00:00Z","timestamp":1563235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To study the development of dizziness, caloric function, and postural sway during long\u2010term observation of untreated vestibular schwannoma patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective review of a prospectively maintained longitudinal cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Patients with vestibular schwannoma undergoing wait\u2010and\u2010scan management were included\u2014specifically, those who did not require treatment during a minimum radiologic follow\u2010up of 1 year. Baseline data and follow\u2010up included magnetic resonance imaging, posturography, bithermal caloric tests, and a dizziness questionnaire. Main outcomes were prevalence of moderate to severe dizziness, canal paresis, and postural instability at baseline and follow\u2010up, as compared with McNemar\u2019s test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 433 consecutive patients with vestibular schwannoma, 114 did not require treatment during follow\u2010up and were included. Median radiologic follow\u2010up was 10.2 years (interquartile range, 4.5 years). Age ranged from 31 to 78 years (mean, 59 years; SD, 10 years; 62% women). Median tumor volume at baseline was 139\u00a0mm<jats:sup>3<\/jats:sup> (interquartile range, 314\u00a0mm<jats:sup>3<\/jats:sup>). This did not change during follow\u2010up (<jats:italic>P<\/jats:italic> =. 446). Moderate to severe dizziness was present in 27% at baseline and 19% at follow\u2010up (<jats:italic>P<\/jats:italic> =. 077). Postural unsteadiness was present in 17% at baseline and 21% at follow\u2010up (<jats:italic>P<\/jats:italic> =. 424). Canal paresis was present in 51% at baseline and 56% at follow\u2010up (<jats:italic>P<\/jats:italic> =. 664).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no significant change in the prevalence of dizziness, postural sway, or canal paresis during conservative management of vestibular schwannoma, while tumor volume remained unchanged. This indicates a favorable prognosis in these patients with regard to vestibular symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599819860831","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T14:10:06Z","timestamp":1563286206000},"page":"846-851","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Long\u2010term Effects of Conservative Management of Vestibular Schwannoma on Dizziness, Balance, and Caloric Function"],"prefix":"10.1002","volume":"161","author":[{"given":"Kathrin Skorpa","family":"Nilsen","sequence":"first","affiliation":[{"name":"Norwegian National Advisory Unit on Vestibular Disorders Haukeland University Hospital Bergen Norway"},{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Haukeland University Hospital Bergen Norway"},{"name":"Department of Clinical Medicine University of Bergen Bergen 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