{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:39:35Z","timestamp":1791549575022,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T00:00:00Z","timestamp":1580774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Cardiovascular risk factors have been associated with benign paroxysmal positional vertigo (BPPV), possibly causing degeneration of the utricular epithelium and subepithelium, but supportive evidence is mixed. This is the first study to examine the association between cardiovascular risk factors and BPPV as they present in the community practice of comprehensive otolaryngology\u2013head and neck surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Cross\u2010sectional case\u2010matched case\u2010control series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>A community practice of otolaryngology\u2013head and neck surgery with 3 clinical offices and a socioeconomically diverse patient population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>Clinical data were collected retrospectively from the electronic health records of a continuous 4\u2010year series of 628 patients with BPPV and age\u2010 and sex\u2010matched controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no statistically significant associations found between BPPV and diabetes, hypertension, dyslipidemia, or body mass index in the study population in pairwise comparisons or multivariable modeling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study suggests that BPPV as encountered in a community ear, nose, and throat practice is not generally associated with cardiovascular risk factors. The possibility that these or other cardiovascular risk factors may be causative in some cases cannot be excluded, though most cases of BPPV appear to be caused primarily by shedding of otoconia from the utricle that is idiopathic or at least in part by unconfirmed noncardiovascular factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0194599820902116","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T04:15:18Z","timestamp":1580789718000},"page":"283-289","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Cardiovascular Risk Factors and Benign Paroxysmal Positional Vertigo in Community Otolaryngology\u2013Head and Neck Surgery"],"prefix":"10.1002","volume":"162","author":[{"given":"Jeffrey M.","family":"Singh","sequence":"first","affiliation":[{"name":"McLaren Health System Pontiac Michigan USA"},{"name":"College of Osteopathic Medicine Statewide Campus System School of Medicine Michigan State University East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William D.","family":"Corser","sequence":"additional","affiliation":[{"name":"College of Osteopathic Medicine Statewide Campus System School of Medicine Michigan State University East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin M.","family":"Monsell","sequence":"additional","affiliation":[{"name":"McLaren Health System Pontiac Michigan USA"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery School of Medicine Wayne State University Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348945206100403"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1969.00770030767020"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816689667"},{"key":"e_1_2_8_5_1","first-page":"681","article-title":"Diagnosis and management of benign paroxysmal positional vertigo (BPPV)","volume":"169","author":"Parnes LS","year":"2003","journal-title":"Can Med Assn J"},{"key":"e_1_2_8_6_1","volume-title":"Pathology of the Ear","author":"Schuknecht HF","year":"1974"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199209000-00006"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199701000-00018"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26115"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016488709109045"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000077227"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.100420"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-9-29"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2013.07.007"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.14639\/0392-100X-1121"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/14992027.2016.1143981"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001800"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.001180"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11936-019-0729-0"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntr313"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.41.4.1149"},{"key":"e_1_2_8_22_1","unstructured":"Centers for Disease Control and Prevention. 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