{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T13:31:07Z","timestamp":1780493467313,"version":"3.54.1"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>We assessed how eustachian tube dysfunction (ETD) changed with endoscopic sinus surgery (ESS) and identified factors associated with improvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Academic center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Patients undergoing ESS for chronic rhinosinusitis with and without nasal polyposis (CRSwNP, CRSsNP) or recurrent acute rhinosinusitis (RARS) completed the Eustachian Tube Dysfunction Questionnaire 7 (ETDQ\u20107) preoperatively and postoperatively at 2 weeks, 6 weeks, 3\u00a0months, and 6\u00a0months. Included in analyses were demographics, comorbidities, Sinonasal Outcome Test 22 (SNOT\u201022), radiographic score, endoscopy score, procedure, and medication use. Regression analysis identified factors associated with improvement, defined as \u0394ETDQ\u20107 &gt;3.5.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 302 patients were studied. ETD prevalence was 68% in CRSsNP, 48% in CRSwNP, and 88% in RARS. Patients with ETD had a mean baseline ETDQ\u20107 of 25.8 \u00b1 8.0 and improved postoperatively at 2 weeks (19.9 \u00b1 8.1, <jats:italic>P<\/jats:italic> &lt;. 001), 6 weeks (17.8 \u00b1 9.3, <jats:italic>P<\/jats:italic> &lt;. 001), 3\u00a0months (16.8 \u00b1 8.5, <jats:italic>P<\/jats:italic> &lt;. 001), and 6\u00a0months (16.4 \u00b1 7.9, <jats:italic>P<\/jats:italic> &lt;. 001). At 6\u00a0months, ETD improved in 89% of patients with CRSsNP, 68% with CRSwNP, and 78% with RARS. On multivariate analysis, ETD improvement was associated with higher preoperative ETDQ\u20107 score (adjusted odds ratio [aOR], 1.12; 95% confidence interval [CI], 1.04\u20101.22; <jats:italic>P<\/jats:italic> =. 030), higher preoperative SNOT\u201022 score (aOR, 1.02; 95% CI, 1.02\u20101.08; <jats:italic>P<\/jats:italic> =. 001), higher preoperative SNOT\u201022 ear subscore (aOR, 1.27; 95% CI, 1.02\u20101.65; <jats:italic>P<\/jats:italic> =. 034), posterior ethmoidectomy (aOR, 1.59; 95% CI, 1.22\u20104.92; <jats:italic>P<\/jats:italic> =. 025), and postoperative corticosteroid spray use (aOR, 1.57; 95% CI, 1.17\u20101.66; <jats:italic>P<\/jats:italic> =. 008).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ETD symptoms often improve following ESS. Factors associated with improvement include higher preoperative disease burden, posterior ethmoidectomy, and postoperative corticosteroid spray.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence:<\/jats:title><jats:p>4<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599820917396","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T13:20:34Z","timestamp":1588080034000},"page":"603-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["The Effect of Endoscopic Sinus Surgery on Eustachian Tube Dysfunction Symptoms"],"prefix":"10.1002","volume":"163","author":[{"given":"Michael T.","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Stanford University School of Medicine Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davood K.","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Stanford University School of Medicine Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Hee","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Daegu Veterans Hospital Daegu Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayakar V.","family":"Nayak","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Stanford University School of Medicine Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zara M.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Stanford University School of Medicine Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer Y.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Stanford University School of Medicine Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Stanford University School of Medicine Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2008.07.010"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22056"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22275"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4193\/RHINOL\/18.050"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22030"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816683342"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240501900214"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin17.165"},{"issue":"1","key":"e_1_2_8_10_1","first-page":"73","article-title":"Eustachian tube dysfunction in chronic rhinosinusitis: pre and post\u2010operative results following endoscopic sinus surgery, a prospective study","volume":"57","author":"Bowles PFD","year":"2019","journal-title":"Rhinology"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23223"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25316"},{"key":"e_1_2_8_13_1","first-page":"S22","article-title":"International consensus statement on allergy and rhinology: rhinosinusitis","volume":"1","author":"Orlandi RR","year":"2016","journal-title":"Int Forum Allergy Rhinol"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26827"},{"key":"e_1_2_8_15_1","article-title":"Acute exacerbations in recurrent acute rhinosinusitis: differences in quality of life and endoscopy [published online December 14, 2019]","author":"Beswick DM","journal-title":"Laryngoscope"},{"issue":"6","key":"e_1_2_8_16_1","first-page":"468","article-title":"Tympanometric changes following nasal antigen challenge in children with allergic rhinitis","volume":"53","author":"O\u2019Connor RD","year":"1984","journal-title":"Ann Allergy"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489418796648"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00464441"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599818821938"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489418798858"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22252"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta18460"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2011.56"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816637845"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001931"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599820917396","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/0194599820917396","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0194599820917396","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:09:21Z","timestamp":1760954961000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0194599820917396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,28]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1177\/0194599820917396"],"URL":"https:\/\/doi.org\/10.1177\/0194599820917396","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,28]]},"assertion":[{"value":"2019-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}