{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:28:04Z","timestamp":1793143684939,"version":"4.5.0"},"reference-count":49,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study is to investigate facial nerve outcomes after microsurgical resection in neurofibromatosis type 2 (NF2) compared to sporadic tumors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Single institutional retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All adult patients with NF2 vestibular schwannoma (VS) or sporadic VS who underwent microsurgical resection from 2008 to 2019 with preoperative magnetic resonance imaging (MRI) and 1 year of postsurgical follow\u2010up were included. The primary outcome measure was postoperative House\u2010Brackmann (HB) facial nerve score measured at first postoperative visit and after at least 10\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 161 sporadic VSs and 14\u00a0NF2 VSs met inclusion criteria. Both median tumor diameter (NF2, 33.5\u00a0mm vs sporadic, 24\u00a0mm, <jats:italic>P<\/jats:italic> =. 0011) and median tumor volume (NF2, 12.4\u00a0cm<jats:sup>3<\/jats:sup> vs sporadic, 2.9\u00a0cm<jats:sup>3<\/jats:sup>, <jats:italic>P<\/jats:italic> =. 0005) were significantly greater in patients with NF2. The median follow\u2010up was 24.9\u00a0months (range, 12\u2010130.1). Median facial nerve function after 1 year for patients with NF2 was HB 3 (range, 1\u20106) compared to HB 1 (range, 1\u20106) for sporadic VS (<jats:italic>P<\/jats:italic> =. 001). With multivariate logistic regression, NF2 tumors (odds ratio [OR] = 13.9, <jats:italic>P<\/jats:italic> =. 001) and tumor volume \u22653\u00a0cm<jats:sup>3<\/jats:sup> (OR = 3.6, <jats:italic>P<\/jats:italic> =. 025) were significantly associated with HB \u22653 when controlling for age, sex, extent of tumor resection, translabyrinthine approach, and prior radiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tumor volume &gt;3\u00a0cm<jats:sup>3<\/jats:sup> and NF2 tumors are associated with poorer facial nerve outcomes 1 year following microsurgical resection.<\/jats:p><\/jats:sec>","DOI":"10.1177\/0194599820954144","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T04:04:08Z","timestamp":1600747448000},"page":"850-858","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Facial Nerve Outcomes After Vestibular Schwannoma Microsurgical Resection in 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