{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T11:41:55Z","timestamp":1790595715118,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Heinsius Houbolt"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Tinnitus is a common hearing\u2010related disorder, which may have a large impact on daily life. With aging populations worldwide, it is important to gain insight in the occurrence of tinnitus at older ages and to understand its relationship with age\u2010related hearing loss. We investigated the prevalence of tinnitus among a general aging population, across age strata and hearing status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Cross\u2010sectional.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>The population\u2010based Rotterdam Study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 6098 participants underwent tinnitus assessment, and 4805 had additional hearing assessment. We determined tinnitus prevalence per 5\u2010year age groups. Hearing impairment was defined as \u226525\u2013dB HL worse ear pure tone average (0.5, 1, 2, 4\u00a0kHz). We investigated with multivariable logistic regression the association between hearing impairment and tinnitus. Tinnitus handicap was assessed in 663 participants with daily tinnitus via the Tinnitus Handicap Inventory\u2013screening version (THI\u2010s).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Tinnitus was prevalent in 21.4% (n = 1304). Prevalent tinnitus was evenly distributed over 5\u2010year age groups. Participants with hearing impairment were more likely to have tinnitus (odds ratio, 2.27; 95% CI, 1.92\u20102.69) as compared with those without hearing impairment. The median THI\u2010s score was 4 (interquartile range, 0\u201010), indicating a slight handicap, and 14.6% of the participants reported a moderate or severe handicap (THI\u2010s \u226516).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a general elderly population, 1\u00a0in 5 persons has tinnitus. Of those with tinnitus, for 1 per 10 persons, the presence of tinnitus interfered with daily life. Participants with hearing impairment were twice as likely to have tinnitus. Despite the age\u2010dependent occurrence of hearing impairment, no such age dependency was found for tinnitus.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0194599820957296","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T04:01:44Z","timestamp":1601352104000},"page":"859-868","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Prevalence of Tinnitus in an Aging Population and Its Relation to Age and Hearing Loss"],"prefix":"10.1002","volume":"164","author":[{"given":"Berthe C.","family":"Oosterloo","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Erasmus University Medical Center Rotterdam The Netherlands"},{"name":"Department of Epidemiology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline H.","family":"Croll","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Erasmus University Medical Center Rotterdam The Netherlands"},{"name":"Department of Epidemiology Erasmus University Medical Center Rotterdam The Netherlands"},{"name":"Department of Radiology and Nuclear Medicine Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Baatenburg de Jong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Kamran","family":"Ikram","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Erasmus University Medical Center Rotterdam The Netherlands"},{"name":"Department of Neurology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Goedegebure","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Erasmus University Medical Center Rotterdam The Netherlands"},{"name":"Department of Epidemiology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2016.05.009"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e31820dd411"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0029966"},{"key":"e_1_2_8_5_1","article-title":"Analysis of the prevalence and associated risk factors of tinnitus in adults","volume":"10","author":"Kim HJ","year":"2015","journal-title":"PLoS One"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmi004"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2017.01221"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32381-9"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32154-2"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S213136"},{"key":"e_1_2_8_11_1","article-title":"Incidence rates of clinically significant tinnitus: 10\u2010year trend from a cohort study in England","volume":"36","author":"Martinez C","year":"2015","journal-title":"Ear Hear"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE20100124"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE20090121"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1715975"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/14992020309078348"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.02.015"},{"key":"e_1_2_8_17_1","article-title":"Hearing in middle age: a population snapshot of 40\u2010 to 69\u2010year olds in the United Kingdom","volume":"35","author":"Dawes P","year":"2014","journal-title":"Ear Hear"},{"issue":"7","key":"e_1_2_8_18_1","first-page":"37","article-title":"Prevalence of tinnitus and audiometric shape","volume":"3","author":"Demeester K","year":"2007","journal-title":"B\u2010ENT"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3766\/jaaa.22.8.7"},{"key":"e_1_2_8_20_1","first-page":"903","article-title":"The inner ear in patients with nasal allergy","volume":"100","author":"Lasisi AO","year":"2008","journal-title":"J Natl Med Assoc"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/01050399309046025"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2013.08.018"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3766\/jaaa.18.3.7"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-020-00640-5"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31816569c4"},{"key":"e_1_2_8_26_1","first-page":"153","article-title":"Psychometric adequacy of the Tinnitus Handicap Inventory (THI) for evaluating treatment outcome","volume":"9","author":"Newman CW","year":"1998","journal-title":"J Am Acad Audiol"},{"key":"e_1_2_8_27_1","author":"ISO","year":"2010","journal-title":"ISO 8253\u20101:2010. 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