{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:05:50Z","timestamp":1791975950686,"version":"4.4.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T00:00:00Z","timestamp":1602547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate associations between self\u2010perceived chemosensory functions of smell, taste, and flavor perception with olfactory\u2010specific quality of life (QoL) in patients with olfactory dysfunction (OD) and whether these associations would be influenced by other factors, such as duration or etiology of smell loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary care, academic center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Olfactory\u2010specific QoL was measured with the Questionnaire of Olfactory Disorders (QOD). The QOD measures the impact of OD on QoL (QOD\u2010negative statements) and the ability of patients to cope with smell loss (QOD\u2010positive statements). Orthonasal olfactory function, patients\u2019 demographics, self\u2010perceived chemosensory perception, and duration and etiology of OD were retrospectively collected in a cohort of patients with quantitative OD. Correlations and multivariable linear regression models were computed to determine possible associations with the outcome measure of QOD\u2010negative and QOD\u2010positive statement scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 133 patients with OD were included. Analysis revealed a positive correlation between self\u2010perceived taste and flavor perception with QOD\u2010negative statement scores, while self\u2010perceived smell showed no significant correlation. Similarly, longer duration of smell loss and higher age were also correlated with higher QOD\u2010positive statement scores. Multivariable regression models confirmed that self\u2010perceived taste was independently associated with the QOD\u2010negative statement score, while age and duration of OD were independently associated with the QOD\u2010positive statement score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that the impact of diminished flavor perception during eating and drinking has a stronger impact on the QoL of patients with OD as compared with decreased orthonasal olfaction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0194599820965242","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T12:36:04Z","timestamp":1602592564000},"page":"1330-1336","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Self\u2010perceived Taste and Flavor Perception: Associations With Quality of Life in Patients With Olfactory Loss"],"prefix":"10.1002","volume":"164","author":[{"given":"David T.","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerold","family":"Besser","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Prem","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunjan","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlene M.","family":"Speth","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Kantonsspital Aarau Aarau Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad R.","family":"Sedaghat","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery College of Medicine University of Cincinnati Cincinnati USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian A.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3758\/BF03202667"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.03.007"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537\u2010200404000\u201000026"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4193\/rhin19.181"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537\u2010200410000\u201000017"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin16.248"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2012.11.008"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.5.497"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.6.635"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjt072"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino10.130"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781420071993\u2010c16"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjz027"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin17.186"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28773"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28258"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240501900606"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjz029"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/b\u20100034\u201091132"},{"issue":"4","key":"e_1_2_10_21_1","first-page":"222","article-title":"\u201cSniffin\u2019 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