{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:25:22Z","timestamp":1789021522024,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH109\u20109M42"],"award-info":[{"award-number":["KMUH109\u20109M42"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to evaluate the hearing outcome of cochlear implantation in patients deafened by M\u00e9ni\u00e8re\u2019s disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective single\u2010institution study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our institutional database of 1400 patients with cochlear implants was reviewed to identify cases with deafness due to M\u00e9ni\u00e8re\u2019s disease. Twenty\u2010nine patients were identified: 24 with unilateral and 5 with sequential bilateral cochlear implants. Pre\u2010 and postoperative speech recognition scores and medical data were extracted from the medical record and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall the mean difference between pre\u2010 and postoperative speech recognition after &gt;1 year was 56% (95% CI, 47.08%\u201064.92%). The mean preoperative monosyllabic word score was 9.5%, and the mean postoperative scores at 1\u00a0month, 3\u00a0months, 6\u00a0months, 1 year, and &gt;1 year were 37.1%, 46.1%, 54.1%, 59.1%, and 66.8%, respectively. Cochlear implantation resulted in improved word scores in all patients regardless of prior medical or surgical treatment (endolymphatic sac, labyrinthectomy). The mean postoperative hearing improvement in patients aged &lt;70 and \u226570 years was 65.26% (95% CI, 54.79%\u201075.73%) and 40.00% (95% CI, 27.22%\u201052.77%). Postoperative word scores in patients with bilateral cochlear implants were not significantly different between the first and second implanted ears or between the monoaural and binaural testing conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cochlear implant in patients deafened by M\u00e9ni\u00e8re\u2019s disease significantly improves word recognition scores regardless of whether medical or surgical treatment is used prior to implantation. The potential improvement in word recognition scores decreases after age 70 years.<\/jats:p><\/jats:sec>","DOI":"10.1177\/01945998211012298","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T12:03:46Z","timestamp":1621339426000},"page":"523-529","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Cochlear Implantation Hearing Outcome in M\u00e9ni\u00e8re\u2019s Disease"],"prefix":"10.1002","volume":"166","author":[{"given":"Chen\u2010Yu","family":"Chien","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Massachusetts Eye and Ear Boston Massachusetts USA"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Harvard Medical School Boston Massachusetts USA"},{"name":"Department of Otorhinolaryngology School of Medicine College of Medicine Kaohsiung Medical University Kaohsiung City"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Kaohsiung Medical University Hospital Kaohsiung Medical University Kaohsiung City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anan","family":"Kulthaveesup","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Massachusetts Eye and Ear Boston Massachusetts USA"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Harvard Medical School Boston Massachusetts USA"},{"name":"Faculty of Medicine Vajira Hospital Navamindradhiraj University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara S.","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Harvard Medical School Boston Massachusetts USA"},{"name":"Department of Audiology Massachusetts Eye and Ear Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Rauch","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Massachusetts Eye and Ear Boston Massachusetts USA"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70102-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2010.05.001"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61161-7"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200604000-00011"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145561319854744"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1179\/1754762814Y.0000000104"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487609107484"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2014.550"},{"issue":"2","key":"e_1_2_8_10_1","first-page":"93","article-title":"Is cochlear implantation an effective treatment for M\u00e9ni\u00e8re\u2019s disease?","volume":"10","author":"Vermeire K","year":"2014","journal-title":"B\u2010ENT"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200305000-00009"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-4356-z"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.5152\/iao.2018.4536"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000247"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000202"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001278"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000343189"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23676"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000920"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshd.2701.62"},{"key":"e_1_2_8_21_1","first-page":"1","article-title":"An expanded test for speech discrimination utilizing CNC monosyllabic words. 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