{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T03:50:52Z","timestamp":1783050652342,"version":"3.54.6"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG6J0331"],"award-info":[{"award-number":["CMRPG6J0331"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CFRPG6J0061"],"award-info":[{"award-number":["CFRPG6J0061"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the association of laryngoplasty, voice therapy, and pneumonia rate in patients with unilateral vocal fold paralysis (UVFP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Population\u2010based retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Data were collected from the LHID2000 (Longitudinal Health Insurance Database 2000), containing the information of 1\u00a0million randomly selected patients in Taiwan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In the LHID2000, we identified 439 patients having new diagnoses of UVFP from 1997 to 2013. We grouped the aforementioned patients according to UVFP treatment and probed the occurrence of pneumonia: 305 patients underwent laryngoplasty or voice therapy, and 134 patients did not undergo treatment. Follow\u2010up procedures were executed for the enrollees until death or December 31, 2013, representing the end of the study period. We assessed the association of UVFP treatment and pneumonia by executing Cox proportional hazards regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The pneumonia cumulative incidence was significantly higher among enrolled patients without treatment than in those receiving treatment (<jats:italic>P<\/jats:italic> &lt;. 001). The pneumonia incidence was significantly lower in patients receiving UVFP treatment (hazard ratio, 0.49; 95% CI, 0.27\u20100.88; <jats:italic>P<\/jats:italic> =. 018), as validated by the Cox proportional hazards model after adjustment. Patients undergoing laryngoplasty with or without voice therapy had a significantly lower incidence of pneumonia at 6\u00a0months and 1, 3, and 5 years, whereas those undergoing voice therapy alone did not.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Laryngoplasty was associated with a lower incidence of short\u2010 and long\u2010term pneumonia in patients with UVFP. Physicians should encourage patients with UVFP at risk of aspiration to receive prompt evaluation as well as treatment.<\/jats:p><\/jats:sec>","DOI":"10.1177\/01945998211015174","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T16:25:50Z","timestamp":1622651150000},"page":"343-349","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Reduction in Short\u2010 and Long\u2010term Pneumonia Rate With Laryngoplasty for Unilateral Vocal Fold Paralysis"],"prefix":"10.1002","volume":"166","author":[{"given":"Cheng\u2010Ming","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Chiayi Chang Gung Memorial Hospital Chiayi"},{"name":"Faculty of Medicine College of Medicine Chang Gung University Taoyuan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao\u2010Te","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Chiayi Chang Gung Memorial Hospital Chiayi"},{"name":"Faculty of Medicine College of Medicine Chang Gung University Taoyuan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geng\u2010He","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Chiayi Chang Gung Memorial Hospital Chiayi"},{"name":"Faculty of Medicine College of Medicine Chang Gung University Taoyuan"},{"name":"Graduate Institute of Clinical Medical Sciences College of Medicine Chang Gung University Taoyuan"},{"name":"Health Information and Epidemiology Laboratory Chiayi Chang Gung Memorial Hospital Chiayi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao\u2010Hsu","family":"Yang","sequence":"additional","affiliation":[{"name":"Health Information and Epidemiology Laboratory Chiayi Chang Gung Memorial Hospital Chiayi"},{"name":"School of Traditional Chinese Medicine College of Medicine Chang Gung University Taoyuan"},{"name":"Department of Traditional Chinese Medicine Chiayi Chang Gung Memorial Hospital Chiayi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuan\u2010Jen","family":"Fang","sequence":"additional","affiliation":[{"name":"Faculty of Medicine College of Medicine Chang Gung University Taoyuan"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Linkou Chang Gung Memorial Hospital Taoyuan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Chan","family":"Lee","sequence":"additional","affiliation":[{"name":"Faculty of Medicine College of Medicine Chang Gung University Taoyuan"},{"name":"Graduate Institute of Clinical Medical Sciences College of Medicine Chang Gung University Taoyuan"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Keelung Chang Gung Memorial Hospital Keelung"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Yen","family":"Liu","sequence":"additional","affiliation":[{"name":"Health Information and Epidemiology Laboratory Chiayi Chang Gung Memorial Hospital Chiayi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng\u2010Hung","family":"Lin","sequence":"additional","affiliation":[{"name":"Health Information and Epidemiology Laboratory Chiayi Chang Gung Memorial Hospital Chiayi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun\u2010Ting","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Chiayi Chang Gung Memorial Hospital Chiayi"},{"name":"Faculty of Medicine College of Medicine Chang Gung University Taoyuan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Shao","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Chiayi Chang Gung Memorial Hospital Chiayi"},{"name":"Faculty of Medicine College of Medicine Chang Gung University Taoyuan"},{"name":"Graduate Institute of Clinical Medical Sciences College of Medicine Chang Gung University Taoyuan"},{"name":"Health Information and Epidemiology Laboratory Chiayi Chang Gung Memorial Hospital 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