{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T15:57:54Z","timestamp":1784735874355,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Endoscopic endonasal transsphenoidal surgery is safe and effective for sellar and parasellar tumor removal. Partial middle turbinate (MT) resection is sometimes performed to optimize the surgical field and facilitate postoperative care. Disturbances in olfaction are concerning because of the lack of randomized studies in this field.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective randomized trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Single academic medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We resected the lower halves of bilateral MTs in the resected group and laterally fractured bilateral MTs in the preserved group. Olfactory outcomes and sinonasal conditions were assessed by using the validated Taiwan Smell Identification Test and Lund\u2010Kennedy Endoscopy Score, respectively. Forty\u2010nine patients were enrolled in the final analysis, of whom 23 underwent partial MT resection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average Taiwan Smell Identification Test result was 36.9 one month after surgery, with a significant change of \u22124.4 \u00b1 3.1 (mean \u00b1 SD; <jats:italic>P<\/jats:italic> &lt;. 01) from baseline. The impact was not significant at 3\u00a0months (\u22122.1 \u00b1 2.6, <jats:italic>P<\/jats:italic> =. 13) or 6\u00a0months (0.3 \u00b1 2.0, <jats:italic>P<\/jats:italic> =. 79). Between the MT resection and preservation groups, there were no significant differences at postoperative 1\u00a0month (<jats:italic>P<\/jats:italic> =. 60), 3\u00a0months (<jats:italic>P<\/jats:italic> =. 86), and 6\u00a0months (<jats:italic>P<\/jats:italic> &gt;. 99). Lund\u2010Kennedy Endoscopy Score was still higher at 3\u00a0months (<jats:italic>P<\/jats:italic> =. 006) after surgery but returned to the preoperative level at 6\u00a0months (<jats:italic>P<\/jats:italic> =. 63).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Endoscopic endonasal transsphenoidal surgery may affect olfaction at 1\u00a0month after surgery, and olfactory function is expected to return after 3\u00a0months. Partial MT resection did not result in additional olfactory loss. It is safe to perform partial MT resection during surgery without compromising the olfactory outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1177\/01945998221086202","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T12:00:46Z","timestamp":1647950446000},"page":"964-970","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Olfactory Outcomes After Middle Turbinate Resection in Endoscopic Transsphenoidal Surgery: A Prospective Randomized Study"],"prefix":"10.1002","volume":"167","author":[{"given":"Pei\u2010Yuan","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mackay Memorial Hospital Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Chun","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mackay Memorial Hospital Taipei"},{"name":"School of Medicine Mackay Medical College New Taipei City"},{"name":"Department of Audiology and Speech Language Pathology Mackay Medical College New Taipei City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Hsuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mackay Memorial Hospital Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiu\u2010Jau","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Medicine Mackay Medical College New Taipei City"},{"name":"Department of Neurosurgery Mackay Memorial Hospital Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun\u2010Kai","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Mackay Memorial Hospital Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuang\u2010Hsuan","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mackay Memorial Hospital Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying\u2010Piao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mackay Memorial Hospital Taipei"},{"name":"School of Medicine Mackay Medical College New Taipei City"},{"name":"Department of Audiology and Speech Language Pathology Mackay Medical College New Taipei City"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2015.29.4206"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-008-0087-5"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21890"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21103"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2015.29.4174"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.09.032"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22416"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.62"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-922014"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1554905"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1253582"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-018-0313-8"},{"key":"e_1_2_8_15_1","first-page":"220","article-title":"Olfaction in patients with nasal polyposis: effects of systemic steroids and radical ethmoidectomy with middle turbinate resection (nasalisation)","volume":"41","author":"Jankowski R","year":"2004","journal-title":"Rhinology"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-018-1450-0"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010021\u201007053\u20104"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2014.28.4097"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940010900704"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20812"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1945892418816841"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23033"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1693124"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21069"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000234933.37779.e4"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/1945892420957505"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/01945998221086202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/01945998221086202","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/01945998221086202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:50:10Z","timestamp":1760968210000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/01945998221086202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1177\/01945998221086202"],"URL":"https:\/\/doi.org\/10.1177\/01945998221086202","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]},"assertion":[{"value":"2021-11-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}