{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:44:04Z","timestamp":1792791844490,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T00:00:00Z","timestamp":1661212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the evolution of voice quality in patients after type I\u2010VI transoral CO<jats:sub>2<\/jats:sub> laser cordectomy (TLC) by using validated voice outcome measures over a 12\u2010month period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective uncontrolled study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Monocenter study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with laryngeal carcinoma who were eligible for type I\u2010IV TLC were prospectively recruited from a tertiary medical center. The following outcomes were assessed throughout the 12\u2010month posttreatment period: Voice Handicap Index (VHI), GRBAS (grade of dysphonia, roughness, breathiness, asthenia, strain), maximal phonation time, fundamental frequency (F0), F0 standard deviation, percentage jitter, percentage shimmer, noise\u2010to\u2010harmonic ratio, and speech fluency. Analyses were performed considering 2 groups of cordectomies: type I\u2010III vs IV\u2010VI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 131 patients completed the evaluations, totaling 76 type I\u2010III and 55 type IV\u2010VI cordectomies. In type IV\u2010VI, breathiness and maximal phonation time significantly worsened from pretreatment to 1 month posttreatment (<jats:italic>P<\/jats:italic> &lt; .05). In the type I\u2010III cordectomy group, VHI, shimmer, roughness, breathiness, and strain significantly improved from pretreatment to 3 months posttreatment, while VHI, F0 standard deviation, shimmer, jitter, grade of dysphonia, roughness, breathiness, and strain improved from baseline to 6 months. Assessments at 12 months posttreatment revealed significant improvements for VHI, shimmer, jitter, noise\u2010to\u2010harmonic ratio, grade of dysphonia, roughness, breathiness, and strain. In the type IV\u2010VI group, VHI significantly improved from baseline to 3, 6, and 12 months posttreatment. Strain improved at 6 and 12 months while roughness improved from baseline to 12 months. Maximal phonation time significantly worsened over the 12\u2010month evaluation period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The effect of TLC on voice quality depends on its type. VHI was identified as the most indicative tool of voice changes irrespective of TLC type.<\/jats:p><\/jats:sec>","DOI":"10.1177\/01945998221114762","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T12:01:42Z","timestamp":1661256102000},"page":"422-428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Voice Quality Outcomes After Transoral CO<sub>2<\/sub> Laser Cordectomy: A Longitudinal Prospective Study"],"prefix":"10.1002","volume":"168","author":[{"given":"Jerome R.","family":"Lechien","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Elsan Hospital  Paris France"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, CHU de Bruxelles CHU Saint\u2010Pierre  Brussels Belgium"},{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"},{"name":"Department of Human Anatomy and Experimental Oncology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology University of Mons  Mons Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Crevier\u2010Buchman","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"},{"name":"Phonetics and Phonology Lab, CNRS UMR7018 Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta P.","family":"Circiu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwan","family":"De Mones","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Pellegrin Hospital University Hospital, CHU Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gr\u00e9goire Vialatte","family":"de Pemille","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aude","family":"Julien\u2010Laferriere","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Saussez","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, CHU de Bruxelles CHU Saint\u2010Pierre  Brussels Belgium"},{"name":"Department of Human Anatomy and Experimental Oncology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology University of Mons  Mons Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Baudouin","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Remacle","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Eich Luxembourg Hospital  Luxembourg Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Hans","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"},{"name":"Phonetics and Phonology Lab, CNRS UMR7018 Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197508000-00003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1986.03780080053011"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0196-0709(93)90050-H"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21528"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199905000-00004"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2012.01.003"},{"issue":"1","key":"e_1_2_8_8_1","article-title":"Multidimensional voice quality evaluation after transoral CO(2) laser cordectomy: a prospective study","volume":"100","author":"Hamzany Y","year":"2021","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21914"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215111002490"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000322592"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2011.04.004"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004050050228"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0279-z"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27932"},{"key":"e_1_2_8_16_1","first-page":"307","article-title":"The Voice Handicap Index: impact of the translation in French on the validation. Article in French","volume":"125","author":"Woisard V","year":"2004","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"e_1_2_8_17_1","volume-title":"Clinical Examination of Voice","author":"Hirano M","year":"1981"},{"issue":"3","key":"e_1_2_8_18_1","first-page":"219","article-title":"Differentiated perceptual evaluation of pathological voice quality: reliability and correlations with acoustic measurements","volume":"117","author":"Dejonckere PH","year":"1996","journal-title":"Rev Laryngol Otol Rhinol"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2019.08.022"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004050000299"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23368"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25582"},{"issue":"1","key":"e_1_2_8_23_1","article-title":"Voice evaluation following endoscopic laser CO(2) cordectomy and conventional cordectomy","volume":"7","author":"Lachowska M","year":"2011","journal-title":"Arch Med Sci"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2019.11.003"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24689"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500085"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e3181b2b36b"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/01945998221114762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/01945998221114762","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/01945998221114762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:04:41Z","timestamp":1760958281000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/01945998221114762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,23]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1177\/01945998221114762"],"URL":"https:\/\/doi.org\/10.1177\/01945998221114762","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,23]]},"assertion":[{"value":"2022-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}