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Studies of patients with previous CP repair who underwent tympanoplasty were included. Meta\u2010analysis of proportions, continuous measures, odds ratios (ORs), and meta\u2010regression were used to analyze graft success and hearing outcomes after tympanoplasty.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 323 patients with CP repair and 1169 controls were included. The proportion of graft success was 86.7% (95% CI, 76.1%\u201094.5%) in patients with CP repair and 88.8% (95% CI, 76.9\u201096.8) in controls. There was no difference in odds of graft success between patients with CP repair and controls (OR, 1.0 [95% CI, 0.5\u20101.8]; <jats:italic>P<\/jats:italic> = .870). Age was not a significant moderator of graft success in patients with CP repair (<jats:italic>r<\/jats:italic> = 0.1 [95% CI, \u22120.2 to 0.3]; <jats:italic>P<\/jats:italic> = .689) or controls (<jats:italic>r<\/jats:italic> = \u22120.0 [95% CI, \u22120.1 to 0.1]; <jats:italic>P<\/jats:italic> = .952). Comparing mean differences between pre\u2010 and postoperative air\u2010bone gap was not statistically significant in patients with CP repair and controls (0.2 dB [95% CI, \u22123.1 to 3.4]; <jats:italic>P<\/jats:italic> = .930). Odds of functional success (postoperative air\u2010bone gap &lt;20 dB) were not different between the groups (OR, 0.8 [95% CI, 0.5\u20101.4]; <jats:italic>P<\/jats:italic> = .450).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This meta\u2010analysis does not endorse anatomic or functional differences between patients with CP repair and controls after tympanoplasty. However, there is a paucity of evidence for younger children. Further studies are warranted to elucidate specific risk factors for tympanoplasty outcomes in young patients with previous CP repair.<\/jats:p><\/jats:sec>","DOI":"10.1177\/01945998221118251","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T12:00:51Z","timestamp":1660046451000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Outcomes of Tympanoplasty After Cleft Palate Repair: A Systematic Review and Meta\u2010analysis"],"prefix":"10.1002","volume":"169","author":[{"given":"Nicolas S.","family":"Poupore","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Medical University of South Carolina  Charleston South Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hussein","family":"Smaily","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery 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