{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:25:53Z","timestamp":1787905553636,"version":"build-2784847793"},"reference-count":75,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T00:00:00Z","timestamp":1661817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Deep brain stimulation (DBS) has considerable efficacy for the motor dysfunction of idiopathic Parkinson's disease (PD) on patient quality of life. However, the benefit of DBS on voice and speech quality remains controversial. We carried out a systematic review to understand the influence of DBS on parkinsonian dysphonia and dysarthria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>A PubMed\/MEDLINE and Cochrane systematic review was carried out following Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) and Population, Intervention, Comparison, Outcome, Timing, and Setting (PICOTS) statements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>Three investigators screened studies published in the literature from inception to May 2022. The following data were retrieved: age, demographic, sex, disease duration, DBS duration, DBS location, speech, and voice quality measurements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From the 180 studies identified, 44 publications met the inclusion criteria, accounting for 866 patients. Twenty\u2010nine studies focused on voice\/speech quality in subthalamic DBS patients, and 6 included patients with stimulation of pallidal, thalamic, and zona incerta regions. Most studies (4\/6) reported a deterioration of the vocal parameters on subjective voice quality evaluation. For speech, the findings were more contrasted. There was an important heterogeneity between studies regarding the voice and speech quality outcomes used to evaluate the impact of DBS on voice\/speech quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The impact of DBS on voice and speech quality significantly varies between studies. The stimulated anatomical region may have a significant role since the stimulation of the pallidal area was mainly associated with voice quality improvement, in contrast with other regions. Future controlled studies comparing all region stimulation are needed to get reliable findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III: evidence from evidence summaries developed from systematic reviews<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/01945998221120189","type":"journal-article","created":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T12:03:09Z","timestamp":1661860989000},"page":"307-318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Deep Brain Stimulation Impact on Voice and Speech Quality in Parkinson's Disease: A Systematic Review"],"prefix":"10.1002","volume":"168","author":[{"given":"Robin","family":"Baudouin","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Universit\u00e9 Paris Saclay)  Versailles France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me R.","family":"Lechien","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Universit\u00e9 Paris Saclay)  Versailles France"},{"name":"Department of Otolaryngology Elsan Hospital  Paris France"},{"name":"Department of Otolaryngology\u2013Head Neck Surgery, CHU de Bruxelles, CHU Saint\u2010Pierre School of Medicine  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Carpentier","sequence":"additional","affiliation":[{"name":"Speech therapy  Paris 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