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All had surgical manipulations on the middle ear or mastoid, or both. Wegener's granulomatosis was suspected because of persistence of the otologic problem. All patients developed pulmonary lesions and had positive diagnoses by biopsy of either the lung, kidney, or upper respiratory mucosa. With timely treatment, all patients have survived.<\/jats:p>","DOI":"10.1177\/01945998780860s409","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T12:39:36Z","timestamp":1461242376000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Wegener's Granulomatosis: Presentation as an Otologic Problem"],"prefix":"10.1002","volume":"86","author":[{"given":"Collin S.","family":"Karmody","sequence":"first","affiliation":[{"name":"Division of Otolaryngology Tufts University School of Medicine Tufts\u2010New England Medical Center Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,22]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"202","article-title":"\u00dcber generalisierte septische Gef\u00e4sserkrankunger Vertrandle","volume":"29","author":"Wegener F","year":"1936","journal-title":"Dtsch Pathol Ges"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5091.265"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1934.03790040090006"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01591560"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(54)90255-7"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.13.1.1"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1961.00740020653003"},{"key":"e_1_2_1_9_1","first-page":"203","article-title":"Granulomatose de Wegener a forme otologique","volume":"90","author":"Bourdiniere J","year":"1973","journal-title":"Ann Otolaryngol (Paris)"},{"key":"e_1_2_1_10_1","first-page":"640","article-title":"Wegener's giant cell granulomatosis treated with corticosteroids","volume":"80","author":"Malcomson KG","year":"1966","journal-title":"J Otolaryngol"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-196902000-00007"},{"key":"e_1_2_1_12_1","first-page":"301","article-title":"Wegener's granulomatosis appearing initially as otitis media","volume":"76","author":"Linthicum FH","year":"1972","journal-title":"Trans Am Acad Ophthalmol Otolaryngol"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197104292841703"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100077136"},{"key":"e_1_2_1_15_1","first-page":"533","article-title":"Wegener's granulomatosis: Pathology and review of the literature","volume":"58","author":"Godman GC","year":"1956","journal-title":"Arch Pathol"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.197.2.90"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-74-1-74"},{"volume-title":"Lehrbuch der speciellen pathologischen Anatomic","year":"1967","author":"Wegener F","key":"e_1_2_1_18_1"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01945998780860S409","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/01945998780860S409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:43:06Z","timestamp":1760956986000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/01945998780860S409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,7]]},"references-count":17,"journal-issue":{"issue":"S4","published-print":{"date-parts":[[1978,7]]}},"alternative-id":["10.1177\/01945998780860S409"],"URL":"https:\/\/doi.org\/10.1177\/01945998780860s409","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[1978,7]]},"assertion":[{"value":"2016-04-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}