{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:41:04Z","timestamp":1760960464219,"version":"build-2065373602"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T00:00:00Z","timestamp":1461283200000},"content-version":"vor","delay-in-days":13017,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1980,9]]},"abstract":"<jats:p>Meniere's disease remains today a poorly understood and difficult\u2010to\u2010manage inner ear problem. Numerous articles have been written about the medical and surgical management of Meniere's disease. Previous authors have suggested that a metabolic abnormality may be a contributing etiologic factor in the disease.<\/jats:p><jats:p>Since 1976, 384 patients with Meniere's disease were seen in the Department of Otolaryngology and Communicative Disorders of the Cleveland Clinic Foundation. In 180 of these patients, the results of a metabolic evaluation were reviewed, including the five\u2010hour glucose tolerance test, lipid profile, free thyroxine index, and the fluorescent treponemal antibody absorption test (FTA\u2010ABS).<\/jats:p><jats:p>The results of these tests suggest that thyroid abnormalities are rare in Meniere's disease. There may be a fairly high false\u2010positive rate in using the FTA\u2010ABS as a screening procedure. Carbohydrate abnormalities are found; however, hypoglycemia was not a major factor in this series of patients. A significant number of patients were found to have lipid abnormalities, and dietary management of these is believed helpful in the medical management of a patient with Meniere's disease.<\/jats:p>","DOI":"10.1177\/019459988008800513","type":"journal-article","created":{"date-parts":[[2016,4,8]],"date-time":"2016-04-08T21:37:35Z","timestamp":1460151455000},"page":"594-598","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The Metabolic Evaluation in Meniere's Disease"],"prefix":"10.1002","volume":"88","author":[{"given":"Sam E.","family":"Kinney","sequence":"first","affiliation":[{"name":"Section of Otology and Neurotology Department of Otolaryngology and Communicative Disorders The Cleveland Clinic Foundation Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,22]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_1_2_1","DOI":"10.1002\/lary.5540890704"},{"doi-asserted-by":"publisher","key":"e_1_2_1_3_1","DOI":"10.1002\/lary.1978.88.1.122"},{"doi-asserted-by":"publisher","key":"e_1_2_1_4_1","DOI":"10.1056\/NEJM196005262622101"},{"key":"e_1_2_1_5_1","first-page":"697","volume-title":"Textbook of Endocrinology","author":"Williams RH","year":"1968"},{"doi-asserted-by":"publisher","key":"e_1_2_1_6_1","DOI":"10.1016\/S0030-6665(20)32785-7"},{"volume-title":"Hyperlipidemia, Clinical Manifestations: Recognition and Treatment","year":"1972","first-page":"15","key":"e_1_2_1_7_1"},{"key":"e_1_2_1_8_1","first-page":"391","volume-title":"Endocrinology and Diabetes","author":"Tzagournis M","year":"1975"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988008800513","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988008800513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:58:29Z","timestamp":1760957909000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988008800513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,9]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1980,9]]}},"alternative-id":["10.1177\/019459988008800513"],"URL":"https:\/\/doi.org\/10.1177\/019459988008800513","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[1980,9]]},"assertion":[{"value":"2016-04-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}