{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T23:21:00Z","timestamp":1784848860712,"version":"3.55.0"},"reference-count":5,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,12,11]],"date-time":"2016-12-11T00:00:00Z","timestamp":1481414400000},"content-version":"vor","delay-in-days":12885,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1981,9]]},"abstract":"<jats:p>A previous study by the authors compared pathologic changes in the mouse sciatic nerve following prolonged <jats:italic>continuous<\/jats:italic> stimulation with either pulsed or direct current. The pulsed current stimulator was found as equally effective yet far safer than the direct current (DC) stimulator. In an attempt to reproduce more accurately the clinical setting, the Ear, Nose, and Throat Device Classification Panel of the Food and Drug Administration requested a prospective, controlled study of repeated DC stimulation at one or more sites along a peripheral motor nerve. Again, repetitive DC stimulation both at one site and at multiple sites of the same nerve produced significant myelin and axon degeneration. The authors conclude that even routine use of the DC stimulator carries with it the potential for permanent nerve damage and muscle paralysis.<\/jats:p>","DOI":"10.1177\/019459988108900515","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T15:19:27Z","timestamp":1483629567000},"page":"767-775","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Myelin and Axon Degeneration following Direct Current Peripheral Nerve Stimulation: A Prospective Controlled Experimental Study"],"prefix":"10.1002","volume":"89","author":[{"given":"Gordon B.","family":"Hughes","sequence":"first","affiliation":[{"name":"Department of Otolaryngology and Communicative Disorders Cleveland Clinic Foundation Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Bottomy","sequence":"additional","affiliation":[{"name":"Baptist Hospital Department of Pathology Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Gary","family":"Jackson","sequence":"additional","affiliation":[{"name":"Otology Group Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Michael E.","family":"Glasscock","sequence":"additional","affiliation":[{"name":"Otology Group Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aristides","family":"Sismanis","sequence":"additional","affiliation":[{"name":"Medical College of Virginia Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,11]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"61","article-title":"Injury to the facial nerve associated with the use of a disposable nerve stimulator","volume":"86","author":"Love JT","year":"1978","journal-title":"ORL"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(80)80018-4"},{"key":"e_1_2_1_4_1","first-page":"100","volume-title":"Facial Nerve Surgery","author":"Esslen E","year":"1977"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197912000-00005"},{"key":"e_1_2_1_6_1","volume-title":"Presented at the Twenty\u2010first Meeting of the Ear, Nose and Throat Device Classification Panel","author":"Hambrecht FT","year":"1980"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988108900515","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988108900515","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:55:47Z","timestamp":1760968547000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988108900515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,9]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1981,9]]}},"alternative-id":["10.1177\/019459988108900515"],"URL":"https:\/\/doi.org\/10.1177\/019459988108900515","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,9]]},"assertion":[{"value":"2016-12-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}