{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:43:33Z","timestamp":1761007413299,"version":"build-2065373602"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,12,11]],"date-time":"2016-12-11T00:00:00Z","timestamp":1481414400000},"content-version":"vor","delay-in-days":12824,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1981,11]]},"abstract":"<jats:p>Thirty\u2010nine patients (median age of 60 years) with carcinoma of the supraglottic larynx (N=16), vocal cord (N=4), and hypopharyngeal wall and pyriform sinus (N=19) were treated by combined conservation surgery and radiation therapy. Thirty\u2010three patients had postoperative treatment, and the remaining six were given preoperative irradiation. The plan was chosen because of clinical and pathologic features known to be fraught with a high incidence of recurrence above the clavicles. Long\u2010term complications occurred in six patients, two of whom died of aspiration pneumonia. Thirty\u2010eight patients completed their treatment and have been followed for a median of 48\u00a0months (1 1\/2 to six years). Survival rates are 56% and 63% for absolute and determinant cases, respectively.<\/jats:p>","DOI":"10.1177\/019459988108900619","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T13:12:02Z","timestamp":1483621922000},"page":"974-978","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Combined Laryngeal Conservation Surgery and Irradiation: Can We Expand the Indications for Conservation Therapy?"],"prefix":"10.1002","volume":"89","author":[{"given":"Helmuth","family":"Goepfert","sequence":"first","affiliation":[{"name":"Departments of head and neck surgery and radiation therapy The University of Texas System Cancer Center M.D. Anderson Hospital and Tumor Institute Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert D.","family":"Lindberg","sequence":"additional","affiliation":[{"name":"Departments of head and neck surgery and radiation therapy The University of Texas System Cancer Center M.D. Anderson Hospital and Tumor Institute Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard H.","family":"Iesse","sequence":"additional","affiliation":[{"name":"Departments of head and neck surgery and radiation therapy The University of Texas System Cancer Center M.D. Anderson Hospital and Tumor Institute Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,11]]},"reference":[{"volume-title":"Otolaryngology","year":"1977","author":"Fletcher GH","key":"e_1_2_1_2_1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197501000-00002"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197511000-00002"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)33120-0"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1978.00790100030006"},{"volume-title":"American Joint Committee for Cancer Staging and End Result Reporting. 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