{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:29:14Z","timestamp":1763036954051,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1983,8,1]],"date-time":"1983-08-01T00:00:00Z","timestamp":428544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1983,8]]},"abstract":"<jats:p>Eosinophilic granuloma is a benign lytic lesion of bone, probably arising from an abnormal proliferation of histiocytes. It may occur within the temporal bone and be confused with more common disorders such as aural polyps or chronic suppurative otitis media. If untreated, the disease may destroy the bony labyrinth and spread to the middle and posterior cranial fossas. Temporal bone lesions may represent only one manifestation of a more extensive multifocal disorder (i.e., Hand\u2010Sch\u00fcller\u2010Christian or Letterer\u2010Siwe disease). From 1967 to 1982, 25 patients with eosinophilic granuloma of the skull were treated in the radiation therapy department of The Methodist Hospital in Houston. Six of these patients had disease involving the temporal bone. After analyzing these cases and reviewing the literature, we conclude that the management of the patient with eosinophilic granuloma in the temporal bone requires a diagnosis based on microscopic examination of the affected tissue, a definition of the extent of disease, therapy consisting of biopsy and low\u2010dosage radiotherapy in the unifocal disease, and careful and continued follow\u2010up.<\/jats:p>","DOI":"10.1177\/019459988309100403","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T06:58:43Z","timestamp":1448434723000},"page":"358-365","source":"Crossref","is-referenced-by-count":20,"title":["Eosinophilic Granuloma in the Temporal Bone and Skull"],"prefix":"10.1002","volume":"91","author":[{"given":"Douglas","family":"Appling","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology and Communicative Sciences Baylor College of Medicine Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herman A.","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Communicative Sciences Baylor College of Medicine Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory A.","family":"Patton","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy Baylor College of Medicine Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1983,8]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"673","article-title":"Polyuria and tuberculosis","volume":"10","author":"Hand A","year":"1893","journal-title":"Arch Pediatr"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-192110000-00004"},{"key":"e_1_2_1_4_1","first-page":"520","article-title":"Acquired hydrocephalus with atropic bone changes, exophthalmos and polyuria","volume":"9","author":"Kay TW","year":"1905","journal-title":"Penn Med J"},{"key":"e_1_2_1_5_1","first-page":"12","article-title":"\u00dcber eingenartige Sch\u00e4deldefekte im Jugendalter","volume":"23","author":"Sch\u00fcller A","year":"1915","journal-title":"Fortschr Geb Roentgenstr"},{"key":"e_1_2_1_6_1","first-page":"849","article-title":"Defects in membranous bones, exophthalmos and diabetes insipidus: An unusual syndrome of dyspituitarism","volume":"3","author":"Christian HA","year":"1920","journal-title":"Med Clin North Am"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1928.00130220002001"},{"key":"e_1_2_1_8_1","first-page":"377","article-title":"Aleuk\u00e4mische Retikulose (Ein Beitrag zu den proliferativen Erkrankungen des Retikuloendothelial apparates)","volume":"30","author":"Letterer E","year":"1924","journal-title":"Frankfurt Z Pathol"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02251373"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1936.01970150003001"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1940.02000030003001"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-196042060-00006"},{"key":"e_1_2_1_13_1","first-page":"479","article-title":"Solitary granuloma of bone simulating primary neoplasm","volume":"16","author":"Otani S","year":"1940","journal-title":"Am J Pathol"},{"key":"e_1_2_1_14_1","first-page":"595","article-title":"Eosinophilic granuloma of bone","volume":"16","author":"Lichtenstein L","year":"1940","journal-title":"Am J Pathol"},{"key":"e_1_2_1_15_1","first-page":"499","article-title":"Eosinophilic or solitary granuloma of bone","volume":"24","author":"Green WT","year":"1942","journal-title":"J Bone Joint Surg"},{"key":"e_1_2_1_16_1","first-page":"99","article-title":"Eosinophilic granuloma of bone","volume":"37","author":"Jaffe HL","year":"1944","journal-title":"Arch Pathol"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-196446010-00007"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196909000-00002"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(73)90149-6"},{"key":"e_1_2_1_20_1","first-page":"475","volume-title":"Tumors of the head and neck","author":"Schnitzer B","year":"1979"},{"key":"e_1_2_1_21_1","first-page":"239","volume-title":"Tumors of bone and cartilage. Atlas of tumor pathology","author":"Spjut HJ","year":"1971"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.5540891001"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1970.00770040050007"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197808000-00009"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1969.00770030565006"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197306000-00005"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197911000-00004"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(76)90721-X"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(76)90711-7"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988309100403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988309100403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:46:15Z","timestamp":1760957175000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988309100403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,8]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1983,8]]}},"alternative-id":["10.1177\/019459988309100403"],"URL":"https:\/\/doi.org\/10.1177\/019459988309100403","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[1983,8]]}}}