{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:48:20Z","timestamp":1790074100661,"version":"4.0.1"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T00:00:00Z","timestamp":1476489600000},"content-version":"vor","delay-in-days":12068,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1983,10]]},"abstract":"<jats:p>Several recent reports have suggested that intravenous (IV) lidocaine is an effective form of therapy to relieve tinnitus; however, many of these studies were not well controlled. A double\u2010blind randomized trial to assess the effectiveness of IV lidocaine on tinnitus was conducted at the University of Washington\u2010affiliated hospitals on a total of 50 patients. Tinnitus was evaluated before and after injection by subjective assessment and audiometric matching. Although 40% of the lidocaine group reported a decrease in tinnitus, over 30% of the lidocaine group reported increased tinnitus after administration of the drug. There was also a high incidence of side effects, including disequilibrium, slurred speech, numbness, and tingling of the extremities in the drug group. The results of the study suggest that the clinical usefulness of IV lidocaine in relieving tinnitus may be less than was previously reported.<\/jats:p>","DOI":"10.1177\/019459988309100514","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T12:24:49Z","timestamp":1500294289000},"page":"550-555","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Treatment of tinnitus with intravenous lidocaine: A double\u2010blind randomized trial"],"prefix":"10.1002","volume":"91","author":[{"given":"Larry G.","family":"Duckert","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Washington School of Medicine Seattle Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas S.","family":"Rees","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Washington School of Medicine Seattle Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,15]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"778","article-title":"A tinnitus identification test","volume":"61","author":"Goodhill V","year":"1952","journal-title":"Ann Otol"},{"key":"e_1_2_1_3_1","first-page":"5","article-title":"On the central effects of Xylocaine with special reference to its influence on epileptic phenomena","volume":"114","author":"Bernhard CG","year":"1954","journal-title":"Acta Physiol Scand"},{"key":"e_1_2_1_4_1","first-page":"583","volume-title":"Advances in pain research and therapy.","author":"Hatangdi CG","year":"1976"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510008511X"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016483609123219"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1937.00650010200005"},{"key":"e_1_2_1_8_1","first-page":"190","article-title":"Intravenous xylocaine in the treatment of attacks of Meniere's disease","volume":"188","author":"Gejrot T","year":"1963","journal-title":"Acta Otolaryngol"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487609120910"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1978.88.9.1477"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988008800422"},{"key":"e_1_2_1_12_1","first-page":"273","volume-title":"Tinnitus, Ciba Foundation Symposium 85.","author":"Emmett JR","year":"1981"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1980.tb02108.x"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1982.00790560009003"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988309100514","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988309100514","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:54:49Z","timestamp":1760968489000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988309100514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,10]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1983,10]]}},"alternative-id":["10.1177\/019459988309100514"],"URL":"https:\/\/doi.org\/10.1177\/019459988309100514","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,10]]},"assertion":[{"value":"1983-01-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}