{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:12:42Z","timestamp":1762866762623,"version":"build-2065373602"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1984,8,1]],"date-time":"1984-08-01T00:00:00Z","timestamp":460166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[1984,8]]},"abstract":"<jats:p>The branchio\u2010oto\u2010renal syndrome, first defined in 1976, is an autosomal dominant disorder characterized by anomalies of the external, middle, and inner ear in association with preauricular sinuses, branchial cleft anomalies, and varying degrees of renal dysplasia, including aplasia. Less frequently expressed phenotypic abnormalities include lacrimal duct aplasia and the stigmata of renal dysgenesis known as Potter facies. Although the precise incidence of the disorder is unknown, it may be more common than is generally appreciated and appears to be distinct from other autosomal dominant otobranchial syndromes. Features of the syndrome expressed in three members of a family are fully illustrated, and other reported cases are compared with these to emphasize the importance of prompt, comprehensive otologic, head and neck, uroradiologic, and genetic evaluation and management.<\/jats:p>","DOI":"10.1177\/019459988409200417","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T07:00:12Z","timestamp":1448434812000},"page":"468-475","source":"Crossref","is-referenced-by-count":8,"title":["Clinical Aspects of the Branchio\u2010oto\u2010Renal Syndrome"],"prefix":"10.1002","volume":"92","author":[{"given":"Peter G.","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Washington University School of Medicine St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Dyches","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Washington University School of Medicine St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Loomis","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Washington University School of Medicine St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1984,8]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"225","article-title":"Dismorphia oto\u2010facio cervicalis familiaris","volume":"9","author":"Fara M.","year":"1967","journal-title":"Acta Chir Plast (Prague)"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1976.tb01546.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320020305"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320070316"},{"key":"e_1_2_1_6_1","first-page":"303","article-title":"The etiology of external ear malformations and its relation to abnormalities of the middle ear, inner ear, and other organ systems. In Gorlin RJ, editor: Morphogenesis and malformation of the ear","volume":"36","author":"Melnick M.","year":"1980","journal-title":"Birth Defects"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197309000-00007"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00454270"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1982.00790560022006"},{"key":"e_1_2_1_10_1","first-page":"1356","article-title":"Severe renal dysgenesis: Produced by a dominant gene","volume":"130","author":"Fitch N.","year":"1976","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(74)80753-5"},{"key":"e_1_2_1_12_1","first-page":"16A","article-title":"Potter syndrome with and without fetal renal abnormality","volume":"13","author":"Barr M.","year":"1976","journal-title":"Teratology"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)39968-9"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/00034894800890S101"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988409200417","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988409200417","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:52:55Z","timestamp":1760968375000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988409200417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,8]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1984,8]]}},"alternative-id":["10.1177\/019459988409200417"],"URL":"https:\/\/doi.org\/10.1177\/019459988409200417","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[1984,8]]}}}