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In cats preloaded with 63\u00a0mg\/kg of pentobarbital, intravenous injection of an additional 60\u00a0mg\/kg reduced, but did not abolish, the later waves of the response. One cat that survived a cumulative dose of 183\u00a0mg\/kg continued to show a well\u2010defined brain stem response. Even doses of barbiturate nearly incompatible with survival do not abolish this response.<\/jats:p>","DOI":"10.1177\/019459988409200616","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T07:00:47Z","timestamp":1448434847000},"page":"685-688","source":"Crossref","is-referenced-by-count":14,"title":["Resistance of the Auditory Brain Stem Response to High Barbiturate Levels"],"prefix":"10.1002","volume":"92","author":[{"given":"Roger R.","family":"Marsh","sequence":"first","affiliation":[{"name":"Department of Otolaryngology and Human Communication Children's Hospital of Philadelphia and the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy C.","family":"Frewen","sequence":"additional","affiliation":[{"name":"War Memorial Children's Hospital London Ontario Canada"},{"name":"Department of Anesthesiology Children's Hospital of Philadelphia and the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie N.","family":"Sutton","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Children's Hospital of Philadelphia and the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William P.","family":"Potsic","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Human Communication Children's Hospital of Philadelphia and the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1984,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197510022931407"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1970.00480290014002"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1961.200.3.417"},{"key":"e_1_2_1_5_1","first-page":"36","volume-title":"Current concepts: The pathophysiology of increased intracranial pressure","author":"Bruce DA","year":"1978"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1975.00490530083009"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/99.3.543"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.3.248"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00455255"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410030416"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1979.00790200029006"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198204000-00005"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1982.57.2.0178"},{"key":"e_1_2_1_14_1","first-page":"350","volume-title":"The pharmacological basis of therapeutics","author":"Harvey SC","year":"1980"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988409200616","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/019459988409200616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:14:33Z","timestamp":1760958873000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1177\/019459988409200616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,12]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1984,12]]}},"alternative-id":["10.1177\/019459988409200616"],"URL":"https:\/\/doi.org\/10.1177\/019459988409200616","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,12]]}}}